龙门县出生缺陷现状调查与干预策略

Status investigation and intervention strategies of birth defect in Longmen county

目的分析龙门县围产期出生缺陷的临床现状,为临床干预制定策略提供依据。方法采用回顾性分析龙门县2012年~2014年孕满28周至生后一周的所有的出生缺陷情况,分析该县各出生缺陷的发病现状并探寻相应的干预措施。结果果分析结果显示,龙门县2012~2014年10107例围产儿中出生缺陷的总发生率为12.27‰,按照发生率的高低居前5位的出生缺陷为指（趾）畸形4.16‰、唇腭裂2.57‰、复合畸形2.08‰、足内翻1.88‰、无脑儿及脑积水1.58‰。结论目前龙门县出生缺陷虽然低于国家的总发生率（l3.7‰）,但仍然偏高,如果采取相应的干预策略,还可以再降低围产儿出生缺陷的发生率,提高出生人口素质。

Objective To analyze the clinical status of perinatal birth defect in Longmen County in order to provide the basis for clinicalintervention strategies. Methods We retrospectively analyze all birth defects pregnant with 28 weeks to one week after the birth from 2012 to 2014 in Longmen county and the status of various birth defects to explore the corresponding intervention measures. Results The results show that the total rate of perinatal birth defects among 10107 cases of Longmen county from 2012 to 2014 was 12.27‰. kccording to the incidence, the top five defects are malformations （toe） lip and palate 2 4.16‰, cleft 57‰,multi- malformation 2. 08‰, strephenopodia1.88 ‰ and anencephalus and hydrocephalus 1.58‰. Conslusion At present although the birth defects of Longmen county is total incidence （13.7‰）, it is stillon the high intervention it can also side. If strategies reduce the perinatal birth defects the birth population qua1 appropriate are taken, incidence of to improve ity.