摘要
阿片类药物被广泛地应用于手术患者围术期镇痛,但其不良反应明显,且大剂量阿片类药物可能引起急性耐受和痛觉过敏,最终导致更严重的疼痛反应。因此,各种非阿片类药物和新技术逐渐被研发和应用于临床,目的是改善患者疼痛和减少阿片类药物的使用,降低阿片相关的不良反应。该文就几种主要非阿片类镇痛药围术期镇痛的应用进展做一综述,以期对患者围术期疼痛进行精确管理,避免过度使用镇痛药物。
Opioids are a kind of classic perioperative analgesics with several dose-related side-effects. Furthermore,large doses of opioids may cause acute tolerance and hyperalgesia,resulting in more serious pain.Therefore various non-opioids and techniques have been explored as part of multimodal analgesia in order to improve pain management and reduce opioid consumption and opioid-related side-effects.Here is to make a review of recent progresses in the study on these non-opioid analgesics,and remind our readers of pre-cise management of perioperative pain and avoid overuse of analgesic drugs .
出处
《医学综述》
2015年第15期2808-2811,共4页
Medical Recapitulate
关键词
非阿片类镇痛药
围术期镇痛
不良反应
Non-opioid analgesics
Perioperative analgesia
Side-effects
