强直性脊柱炎的早期临床特点

The Early Clinical Features of Ankylosing Spondylitis

目的探讨强直性脊柱炎的早期临床特点。方法选择2010年2月至2013年2月在湖北医药学院附属东风医院确诊的强直性脊柱炎患者75例作为研究组,同期选择本院的健康体检者75例作为对照组,两组都进行了X线诊断与测量,同时研究组进行了X线评级与临床特点的调查。结果研究组X线征象主要表现为关节间隙变窄、股骨头基底部骨赘形成、髋臼囊变。75例患者X线征象评分为0分0例,1分23例,2分30例,3分17例,4分5例,评分2~3分占70.7%。研究组的髋臼直径与股骨头直径显著少于对照组[（6.0±0.5）cm比（6.4±0.5）cm,（5.5±0.4）cm比（5.7±0.5）cm,P〈0.05]。结论 X线能显示强直性脊柱炎患者骶髂关节细微结构,结合临床特点更加有利于进行临床的诊断。

Objective To investigate the early clinical features of ankylosing spondylitis .Methods A total of 75 cases of diagnosed ankylosing spondylitis in Hubei Medical College Affiliated Hospital from Feb . 2010 to Feb.2013 were selected as the observation group ,and another 75 healthy people in the hospital dur-ing the same period were included as the control group.All cases received X-ray radiation diagnosis and measurements,while X-ray rating and clinical characteristics ratings were conducted on the observation group.Results The main X-ray features of the observation group were joint space narrowing,femoral basal osteophyte formation,acetabular bone cystic degeneration.X-ray ratings of the 75 cases：0 case of 0 score,23 cases of 1 score,30 cases of 2 scores,17 cases of 3 scores,and 5 cases of 4 scores,the score of 2-3 score accounted for 70.7%.The diameter of the femoral head and acetabular hip of the observation group were sig-nificantly less than the control group[（6.0 ±0.5） cm vs （6.4 ±0.5） cm,（5.5 ±0.4） cm vs （5.7 ± 0.5） cm,P〈0.05].Conclusion The X-ray can show fine structure of sacroiliac joint of the ankylosing spondylitis patients,which is more conducive to the clinical diagnosis combined with clinical features .