手术联合降钙素治疗不稳定型股骨转子间骨折患者的疗效观察

Clinical study of PFNA combined with calcitonin in patients of femoral intertrochanteric fracture

目的比较降钙素联合股骨近端防旋转髓内钉(PFNA)与单纯行PFNA治疗不稳定型股骨转子间骨折的临床疗效。方法采用随机数字表的方法,将98例不稳定型股骨转子间骨折患者分为实验组和对照组各49例,实验组行PFNA手术并给予鲑鱼降钙素治疗,对照组仅行PFNA手术。术后观察两组患者的骨折愈合情况,记录患者Harris评分及住院时间,记录手术相关并发症。比较两组患者骨折愈合时间、住院时间、术后开始负重时间和并发症发生率等,采用Harris评分进行患者髋关节功能的评价。结果实验组各项指标都显著地优于对照组(P<0.05),实验组髋关节功能优良率显著高于对照组(P<0.05)。结论股骨近端防旋髓内钉(PFNA)微创手术联合降钙素治疗不稳定型股骨转子间骨折,可缩短患者住院时间,疗效可靠,能促进患髋骨愈合及术后髋关节功能康复。

Objective To compare the clinical outcomes between proximal femoral nail antirotation（PFNA）com- bined with calcitonin and PFNA only for the treatment of unstable intertrochanteric fractures in patients. Methods By using the method of random number table, 98 patients with intertrochanteric fracture were divided into two groups. Patients in experimental group were treated with PFNA combined with caleitonin. While patients in control group were treated with PFNA only. The basic indices of patients, as the postoperativeload time, the time of hospitalization, fracture healing time and complication rate were observed. The curative effect was evaluated by Harris hip function score. Results The basic indices in experimental group were significantly better than those in control group. The patients＂ functional recovery of hip joint was significantly higher than those in control group. Conclusion In treating unstable femoral inter- trochanteric fractures, PFNA combined with calcitonin can efficiently reduce the time in bed, positively prevent fixation failure, accelerate union of fracture and facilitate functional recovery.