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图像引导自适应放疗在宫颈癌治疗中的应用 被引量:5

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摘要 目的观察图像引导自适应放疗(IGART)在宫颈癌治疗中的应用效果。方法接受放疗的宫颈癌患者14例,借助4D CT扫描图像设计放疗计划及剂量,放疗过程中采用锥形束CT(CBCT)扫描,获取用于IGART的图像。放疗前采用CBCT进行位置验证扫描,并将获取的CBCT图像与计划CT图像进行3D-3D配准,测量患者的摆位误差。借助CBCT图像勾画放疗过程中的肿瘤靶区(PTV),评价计划靶区(PTV)对GTV的覆盖情况。结果 14例患者共执行131次CT扫描,其中治疗前扫描95次,在线匹配后验证扫描36次。在治疗前95次扫描中,患者头脚、前后和左右方向的摆位误差分别为(0.38±0.07)、(0.30±0.09)、(0.28±0.10)cm。36次验证扫描后,患者头脚、前后和左右方向的摆位误差均减少(P均<0.05)。患者分次放疗期间,CBCT图像与计划CT图像匹配修正前GTV溢出PTV 6次,未覆盖率为6.3%(6/95),匹配修正后分别为2次和2.1%。结论 IGART用于宫颈癌治疗可减少并修正患者的摆位误差,降低肿瘤靶区脱靶的发生率,缩小临床靶区的外扩边界。
出处 《山东医药》 CAS 北大核心 2015年第27期38-39,共2页 Shandong Medical Journal
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参考文献13

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二级参考文献4

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