布托啡诺复合舒芬太尼在创伤患者术后镇痛中的应用

Effects of butorphanol and sulfentanty on postoperative patient controlled intravenous analgesia in trauma patients

目的：比较单纯用布托啡诺、舒芬太尼和布托啡诺复合舒芬太尼用于创伤患者术后自控静脉镇痛（ PCIA）的临床效果。方法120例ASAⅠ～Ⅲ级创伤患者，均采用气管插管静脉复合麻醉，随机分为布托啡诺组（ B组）、舒芬太尼组（ S组）和布托啡诺复合舒芬太尼组（ BS组），每组40例。观察术后6、12、24、48 h镇痛、镇静效果，患者PCIA的给药次数和不良反应情况。结果三组PCIA方案均能达到良好镇痛目的，各时间点VAS评分差异无统计学意义（P＞0．05）。 BS组不良反应发生率较低，患者满意度更高（ P＜0.05）。结论布托啡诺复合舒芬太尼是一种较理想的创伤患者术后镇痛方法。

Objective To observe the analgesic effects and side effects of butorphanol and sulfentanty combination on postop-erative patient controlled intravenous analgesia （ PCIA） in trauma patients.Methods One hundred and twenty trauma patients requi-ring PCIA postoperatively were randomly divided into 3 groups.Butorphanol group （ Group B） , sulfentanty group（ Group S） , butorpha-nol and sulfentanty group（Group BS）.The following indexes were noted at 6, 12, 24, and 48 hours respectively after operation：pain VAS score, Ramsay sedation score, frequency of self-controlled medication and adverse reactions.Results The VAS scores in three groups were not significantly different（P〉0.05）.Adverse reactions in Group BS are lower than that in the other two groups（P〈0.05 ） .Conclusion Butorphanol and sulfentanty combination has good effects on relieving postoperative pain with fewer side effects in trama patients.