病毒性肝炎空腹与餐后血清TBA水平临床分析

Clinical analysis of serum TBA level of limosis and 2 hours after meal with viral hepatitis

目的分析空腹与餐后 2小时血清总胆汁酸 (TBA)在病毒性肝炎中的变化水平。方法对 36例病毒性肝炎患者及健康对照组均用化学比色法测定空腹和餐后静脉血清TBA含量 ,并进行分组比较。结果病毒性肝炎患者各组空腹和餐后 2小时血清TBA含量显著高于正常对照组 ,(P <0 0 5、P <O 0 1) ;活动性肝硬变、慢性肝炎中度和急性黄疸型肝炎患者血清TBA含量餐后 2小时较空腹明显升高 (P <O 0 1,P <0 0 5 ) ;活动性肝硬变和慢性肝炎中度、轻度患者TBA异常率餐后 2小时较空腹增高 ,其异常率为 :活动性肝硬变 10 0 %、92 % ,慢性肝炎中度 71%、5 7% ,慢性肝炎轻度 5 6 %、4 4 % ,急性黄疸型肝炎异常率均为10 0 %。结论血清TBA测定是衡量肝细胞损害程度的重要指标 ,餐后

Objective To analyze the changes of serum TBA of limosis and 2 hours after meal with viral hepatitis Methods The serum TBA of 36 patients with viral hepatitis were measured by chemical emzyme specerophotometry,and compared with the normal groups.Results The serum TBA in patients with viral hepatitis were obviously higher than that of the normal groups of limosis and 2 hours after meal(p<0.05,p<0.01).The serum TBA of patients with active posthepatitic cirrhosis?moderate chronic hepatitis and acute icterohepatitic in 2 hours after meal were significantg higher than that in limosis(P<0.01?p<0.05).The rate of abnormity of patients with active posthepatitic cirrhosis?moderate and mild chronic hepatitis in 2 hours after meal were higher than that in limosis(active posthepatitic cirrhosis:100%,92%;moderate chronic hepatitis:71%,57%;mild chronic hepatitis:56%,44%;acute icterohepatitic:100%,100%)Conclusion The measurement of serum TBA is an important index of assessing the damage degree of livercells.The measurement of serum TBA of 2 hours after meal is more important for the patients with active posthepatitic cirrhosis and chronic hepatitis.