血管周围脂肪组织功能障碍与脉胀病(高血压)病机辨析

Analysis of the dysfunction of perivascular adipose tissue and the pathogenesis of vessel distention(hypertension)

血管周围脂肪组织具有生物活性,可分泌众多脂肪因子、细胞因子等活性物质,对血管功能具有明确的调节作用。"脉胀"是一个中医概念,是指脉搏胀满、血压升高的一类疾病。血管周围脂肪组织所分泌的各种活性物质是中医"气"的微观物质之一,它可通过影响"气"的正常功能而导致气血失和、血脉病变,促进脉胀(高血压病)的形成和发展。

Perivascular adipose tissue is bioactive, which can secretes many cytokines and adipocytokines, and has a clear regulation function on vessels. Vessel distention is a concept of traditional Chinese medicine, which specially means that the blood vessels are full and distent, and the blood pressure is high. These bioactive substances which secrete from perivascular adipose tissue are one of the micro-substances of qi in traditional Chinese medicine. They can cause qi-blood disharmony and vasculopathy by the regulation of physiological functions of qi, so that promote the formation and progression of vessel distention finally.