摘要
类风湿性关节炎(RA)是一种全身性、难治性、自身免疫性疾病,属于中医"痹症"范畴。中药活性成分治疗RA有悠久的临床应用历史。近年来,针对中药活性成分抗RA作用机制开展了大量的实验研究工作,主要表现在抗炎、镇痛和免疫调节等多方面。文章收集20余篇文献资料,从中药活性成分的干预作用方面,总结了中药活性成份对类风湿关节炎滑膜细胞作用机制的研究进展,归纳了研究中存在的问题和难点,并提出了研究思路。
Rheumatoid Arthritis (RA) is a refractory systemic autoimmune disease and in traditional Chinese medicine (TCM), RA belongs to the arthralgia syndrome. Clinical application of traditional Chinese medicine active components in the treatment of RA has a long history. In recent years, a big amont of researches had been done on the mechanism of treating RA by traditional Chinese medicine active components, in the following aspects such as anti-inflammatory, analgesic and immunomodulatory. In this article, we collected more than 20 documents from the aspect of the intervention of TCM active components, comprehensively reviewed the research about action mechanism of TCM active components in treating RA synovial cells, and summarized the existing problems and difficulties in the research, and put forward the thought of research.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2015年第8期2862-2864,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(No.81360580)
贵州省社会发展攻关计划课题(No.黔科合SY[2010]3102号)
贵州省省长基金课题[No.黔省专合字(2012)33]
贵州省中医药管理局课题(No.QZYY2012-21)
贵州省科技创新人才团队项目[No.黔科合人才团队(2013)4033]~~
关键词
类风湿关节炎
滑膜细胞
中药活性成份
综述
Rheumatoid arthritis
Synovial cells
TCM active components
Review