武汉市洪山区居民代谢综合征流行病学调查及其主要危险因素分析

Epidemiological investigation on metabolic syndrome and its main risk factors among residents in Hongshan District of Wuhan City

目的调查武汉市洪山区15岁以上居民代谢综合征（MS）的流行现状并分析其主要危险因素。方法于2013年6月—2014年1月采用分层多级随机抽样方法,从武汉市洪山区居民中抽取调查样本963例,进行问卷调查、体格检查及血生化指标的检测。结果武汉市洪山区居民代谢综合征的患病率为18.69%（180/963）,男性明显高于女性（21.38%vs.16.20%）,但差异无统计学意义（χ^22.907,P〉0.05）;MS患病率随年龄的增长而增加,青年组男性高于女性（21.6%vs.4.5%,χ^24.604,P〈0.05）,而中年组和老年组女性明显高于男性;45.5%的研究对象合并≥2种的代谢异常;多因素Logistic回归分析显示,TG、FPG、高血压家族史、腰围、收缩压、年龄、心率与MS存在正相关（OR=2.691、1.774、1.767、1.156、1.055、1.026、1.024,P〈0.05）,可视为MS的危险因素;文化水平、HDLC与MS存在负相关（OR=0.097、0.850,P〈0.05）,可视为MS的保护因素。结论武汉市洪山区有很大比例成人患有MS,年龄、高血压史、TG、HDL-C、FPG、腰围、心率、收缩压、文化水平均为相关危险因素,MS已成为本地区一个重要的公共卫生问题,应引起高度重视。

Objective To investigate the prevalence and risk factors of metabolic syndrome （MS） in the aged over 15 years in Hongshan District of Wuhan city. Methods From June 2013 to January 2014, the residents are stratified with multi- stage random sampling method, from Hongshan District of Wuhan city sampled 963 cases to receive questionnaire, physical examination and blood test. Results Residents from Hongshan district of Wuhan city ＇ s prevalence of metabolic syndrome was 18.69% （ 180/963 ） , male was higher than female （21.38% vs. 16.20% ） , but the difference was not statistically signifi- cant （χ^2 = 2. 907, P 〉 0.05） ; MS prevalence rate increased with age, male was higher than that in young group female （21.6% vs. 4.5% , χ^2 = 4. 604, P 〈 0.05 ） , and in the middle-aged and elderly patients, females were higher than males; 45.5% subjects with more than 2 kinds of anomalies; multivariate Logistic regression analysis revealed that there were positive correlation between TG, FPG, family history of hypertension, waist circumference, systolic blood pressure, heart rate, age and MS （OR=2.691, OR=1.774, OR=1.767, OR=1.156, OR=1.055, OR=1,026, OR=l.024,P 〈0.05）, which can be regarded as risk factors for MS ; there is a negative correlation between MS and HDL-C, the cultural level （ OR = 0. 097, OR = 0. 850, P 〈 O. 05 ） , which can be regarded as a protective factor for MS. Conclusion Hongshan District of Wu- ban City has a large proportion of the adult patients with MS, age, history of hypertension, TG, HDL-C, FPG, waist circum- ference, heart rate, systolic blood pressure, cultural level are related risk factors, MS has become the region an important public health problem, which should pay more attention on it.