缺血性脑血管病相关因素分析及认知功能的临床研究

Clinical study of functional analysis and cognitive factors related to ischemic cerebral vascular dis-ease

目的：研究分析缺血性脑血管病相关因素及认知功能的相关性。方法将66例缺血性脑血管病患者分为三组，其中高危组有20例患者，中危组24例，轻危组22例，对三组患者全部进行脑血管血流动力学检测及认知功能评定，观察对比各组患者检测及评定结果。结果三组患者经颅多普勒超声（TCD）检查结果对比以高危组患者异常比例（100%）最高（P ﹤0.05），且各组患者的蒙特利尔量表评定情况对比差异也有统计学意义（P ﹤0.05）。结论缺血性脑血管病患者相关因素与认知功能密切相关，危险因素增多可导致认知功能障碍及 TCD 异常加重。

Objective To study the correlation analysis of the related factors of ischemic cerebral vascular disease and cognitive function. Methods Sixty-six cases of patients with ischemic cerebrovascular disease were divided into three groups,with 20 cases in high risk group,24 cases in medium risk group and 22 cases in mild risk group. All patients were detected and cognitive function assessment of cerebrovascular hemodynamics,the results were compared. Results In terms of the transcranial Doppler（TCD）examination results,high risk group patients with abnormal ratio was the highest（100% ,P ﹤ 0. 05）,and each group of patients in Montreal scale also had significant difference（P ﹤0. 05）. Conclusions The related factors of the patients with ischemic cerebrovascular disease are closely correlated with cognitive functions,and increasing risk factors may lead to cognitive dysfunction and abnormal TCD exacerbation.