56例阻塞性呼吸暂停综合征患者冠脉造影结果分析

Angiographic analysis of 56 patients with obstructive sleeping apnea syndrome

目的：分析56例阻塞性呼吸暂停综合征患者冠脉造影结果。方法选取阻塞性呼吸暂停综合征（OSAS）患者56例作为 OSAS 组；选取同期门诊体检患者51例作为对照组；选取同期无阻塞性呼吸暂停综合征冠心病患者36例作为非 OSAS 合并冠心病组，OSAS 组患者及非 OSAS 合并冠心病组行整夜多导睡眠（PSG）检查，对OSAS 组和对照组进行血压、血糖、体质量指数（BMI）、高密度脂蛋白（HDL）、低密度脂蛋白（LDL）、总胆固醇进行检查，对所有患者均行冠状动脉造影。结果 OSAS 组与对照组相比较，高血压例数（67.86%）、冠心病例数（55.36%）更高，OSAS 组 BMI（26.62±4.32）高于对照组（22.15±3.14），冠脉造影显示 OSAS 组合并冠心病三支病变（48.39%）大于非 OSAS 合并冠心病组（22.22%），闭塞段长度（20.51±8.45）长于非 OSAS 合并冠心病组（13.98±5.89），Gensini 评分（52.77±23.41）大于非 OSAS 合并冠心病组（26.98±11.32），差异有统计学意义（P ﹤0.05）。结论 OSAS 患者更易并发冠心病，且冠状动脉损伤更加严重。

Objective To analyze the angiographic manifestations of 56 patients with obstructive sleeping apnea syndrome. Methods Fifty-six patients with OSAS were chosen as OSAS group,and 51 cases got regular physical examination were chosen as control group,36 CHD cases without OSAS were chosen as CHD without OSAS group. OSAS group and CHD without OSAS group received PSG,and blood pressure,blood glucose,BMI,HDL,LDL,total cholesterol were taken in OSAS group and control group. Coronary artery angiography was conducted among every patient. Results Compared to control group,hypertension,CHD cases and BMI of OSAS group were more. Besides,triple vessel disease,length of blocking, Gensini score of OSAS group with CHD were more than CHD without OSAS group. The diffenrence was significant（P ﹤0. 05）. Conclusions OSAS patients are easier to suffer from CHD,and the injuries of coronary arteries are more serious.