糖尿病OGTT实验90min内血糖胰岛素C肽变化规律的探讨

Study of blood glucose,insulin,and C- peptide change for diabetes taking OGTT test within 90 minute

目的探讨OGTT实验糖负荷后90min内血糖、胰岛素、C肽的变化规律。方法分别观察正常人与糖尿病患者在OGTT实验糖负荷后前半小时内每隔五分钟抽样一次和糖负荷1小时后半小时内每隔5min抽样一次,抽取肘静脉血,检测葡萄糖(G),胰岛素(I),C肽(C)数值,并探讨正常人与糖尿病患者糖负荷后90min内血糖、胰岛素、C肽变化规律的区别。结果与正常人相比,糖尿病患者在OGTT实验糖负荷后90min内血糖、胰岛素、C肽有各自的变化规律,血糖逐渐升高,胰岛素、C肽峰值降低且延迟。结论 OGTT实验糖负荷后90min可反映胰岛β细胞的功能状态,可以反映人体的糖代谢功能。

Objective To study the different parameters, such as blood glucose, insulin, and C - peptide, when diabetes taking OGTT test within 90 minutes. Methods Observed these parameters after diabetes take OGTT test immediately and after one hour, take measure by draw elbow venous blood every five minutes. Measure blood glucose, insulin, and C- peptide value and compare these values between diabetes and normal people. Results Compare with normal people, these three parameters of diabetes has their own changes, blood glucose increase, but others decrease and delay. Conclusion After 90 minutes, pancreatic βcell can show their function. And reflect the metabolic function of human body.