期刊文献+

COPD患者病情变化与瘦素及IL-6水平的相关性研究进展 被引量:8

Study on the Correlation between the Disease Condition Changes and Leptin,IL-6 Level in COPD Patients
下载PDF
导出
摘要 慢性阻塞性肺疾病(COPD)是一种常见的不可逆性的慢性肺部疾病,患病率高,但可预防和治疗。COPD包括慢性支气管炎和肺气肿两类。COPD患者的重要特征之一是体质量减轻,这与血清瘦素和白细胞介素6(IL-6)水平相关,且瘦素可能是COPD急性加重期的炎性标志物并可评估疾病的严重程度。该文就COPD的临床症状、流行病学、发病机制、急性加重期及稳定期COPD患者的病情变化与血清瘦素及IL-6水平的相关性研究予以综述。 Chronic obstructive pulmonary disease(COPD),is a kind of common irreversible chronic lung disease,prevalence,but prevention and treatment are available.COPD includes two categories:chronic bron-chitis and emphysema.One of the important features of COPD patients is weight loss,which is correlated with serum levels of leptin and IL-6.The leptin may be inflammatory markers of acute exacerbation of COPD and can be used to assess the severity of the disease.Here is to make a review of the correlation between the clini-cal symptoms of COPD, epidemiology, pathogenesis, acute exacerbation and stable stage of COPD patients with changes in serum leptin and IL-6 levels.
出处 《医学综述》 2015年第14期2524-2526,共3页 Medical Recapitulate
关键词 慢性阻塞性肺疾病 瘦素 白细胞介素6 临床症状 预防 Chronic obstructive pulmonary disease Leptin Interleukin-6 Clinical symptoms Prevention
  • 相关文献

参考文献19

二级参考文献102

共引文献259

同被引文献114

  • 1苏惠萍,武维屏,冯淬灵,周绍忠,田秀英,金晨曦.益气活血化痰法对慢性阻塞性肺疾病患者血清中TGF-β_1及IL-8表达的影响[J].北京中医药大学学报,2005,28(1):48-51. 被引量:33
  • 2徐锡鸿,孔繁智,虞小霞,沈金美,杨加珞,石玲,顾佩芳,章建民,任佩天,党聚兴,柴秀娟,李端阳.大鼠肺气虚“证”模型的建立[J].中医杂志,1994,35(4):230-232. 被引量:16
  • 3刘景艳,修清玉.细胞因子在慢性阻塞性肺疾病发病中的作用[J].国外医学(呼吸系统分册),2005,25(6):420-422. 被引量:95
  • 4杨晶,邵杰敏,张爱丽,韩晓雯.炎症因子与慢性阻塞性肺疾病[J].临床荟萃,2007,22(12):911-912. 被引量:21
  • 5Gao J,Li J,Zheng SR,et al.Anti-inflammatory and immunoregulatory effects of Yupingfeng powder on chronic bronchitis rats[J].Chin J Integr Med,2013,19(5):353.
  • 6Yang E,Altes T,Anupindi SA.Early Mycoplasma pneumoniae infection presenting as multiple pulmonary masses:an unusual presentation in a child[J].Pediatr Radiol,2011,38(4):477.
  • 7Belling hausen I, Sudowe S, Konig B, et al. Intedeukin-10-trea- ted dendritic cells do not inhibit Th2 immune responses in ovalbu- mitt/Mum-sensitized miee[ J]. Int Arch Allergy Immunol, 2012, 141(1) :61 -69.
  • 8Emami Ardestani M, Zaerin O. Role of Serum? Interleukin 6, Al- bumin and C-Reactive Protein in COPDPatients [ J ]. Tanaffos, 2015, 14(2) :134 -140.
  • 9Kalaycloglu E, G~kdeniz T, Aykan A,et al. Evaluation of Left Ventrieular Function and its Relationship With MultidimensionalGrading System ( BODE? Index) in Patients With COPD [ J ]. COPD, 2015, 12(5) :568 -574.
  • 10Tanrlverdi H, Omek T, Erboy F, et al. Comparison of diagnostic values of procalcitonin, C-reactive protein and blood neutrophil/ lymphocyte ratio levels in predicting bacterial infection in hospital- ized patients with acute exacerbations of COPD [ J ]. Wien Klin Wochensehr, 2015, 127(19-20) :756 -763.

引证文献8

二级引证文献87

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部