系统性红斑狼疮患者发生骨质疏松的危险因素及其防治对策

Risk Factors and Prevention Measures for Osteoporosis in Patients with Systemic Lupus Erythematosus

随着诊断技术及治疗水平的提高,系统性红斑狼疮(SLE)患者的存活率逐渐上升,生活质量也得到极大的改善。骨质疏松症作为SLE常见的并发症之一,不仅影响SLE患者的日常生活,甚至继发严重骨折,而危及患者的生命。糖皮质激素的应用是SLE并发骨质疏松的最常见原因,充分认识SLE患者发生骨质疏松的危险因素,为治疗药物的选择提供理论基础,对于提高患者的生存率及生活质量具有重要作用。该文就SLE患者发生骨质疏松的主要危险因素和防治对策予以综述。

With the improvement of diagnostic techniques and therapeutic levels,the survival of patients with systemic lupus erythematosus （ SLE ） has increased gradually and the quality of life has been greatly improved.Osteoporosis is one of the complications of SLE,affecting the quality of life for patients with SLE and even endangers the life of patients in case of severe fracture.Glucocorticoids usage is the most common cause of osteoporosis in SLE patients.To improve the survival rate and the life of patients with SLE,it is important to study the risk factors of SLE with osteoporosis and provide a theoretical basis for the choice of medication.Here is to make a review of the various risk factors,preventative and therapeutic strategies for os-teoporosis of SLE patients.