针刺大肠合募配穴对功能性便秘影响随机对照研究

A Cinical Randomized Controlled Trial of Acupuncture at the Combination of Lower-he Point and Front-mu Point of Large Intestine Meridian for Treating Functional Constipation

目的:观察针刺大肠合募配穴(天枢配上巨虚)及非经非穴点对功能性便秘的影响,评价针刺治疗功能性便秘的临床疗效,为针刺治疗本病选穴方案提供临床依据。方法:将符合纳入标准的72例患者,按照随机、单盲、对照的原则,分为大肠俞募配穴组(治疗组)和非经非穴组(对照组),每组36例。两组均每日针刺1次,每次30 min,每周治疗5次为1个疗程,连续治疗4个疗程。分别于治疗前、治疗完成时,由患者填写周排便次数、便秘症状评分,评价两者疗效的差异性。结果:治疗组治疗前后周排便次数、便秘各症状及总积分,均有显著性差异(P<0.01)。对照组治疗前后排便困难积分差异,没有统计学意义(P>0.05);下坠不尽感积分差异,有统计学意义(P<0.05);其余各项积分差异均有显著性差异(P<0.01)。治疗后,两组组间比较结果显示,频率积分差异有统计学意义(P<0.05);周排便次数、排便困难积分、腹胀症状积分差异,有显著性差异(P<0.01),但在总积分和粪便性质、排便时间、下坠不尽感积分,差异无统计学意义(P>0.05)。结论:针刺大肠俞募配穴与非经非穴,均可有效治疗功能性便秘。两者均能有效改善患者的症状,但前者的改善程度明显优于后者。

Objective：To observe the efficiency of acupuncture at acupoiuts of ST25 matching ST37 in the treatment of patient with functional constipation （ FC ） and to compare with that of unspecific acupuncture, in order to provide clinical basis for optimizing a better treatment. Methods ： 72 patients were randomly divided into a treatment group and a control group, each of the group contained 36 patients. The treatment group was treated by acupuncture at acupoints of ST25 matching ST37 （ the combination of lower- he point and front-mu point of large intestine meridian ）, while the control group was treated by unspecific acupuncture. All patients received a total of four treatment cycles, each of which consisted of acupuncture once a day （ 0.5 h each time ） for one week （ five times ） .Immediately before and after the treatment, all patients were requested to fill in several scales, such as stool frequency of a week, scores of constipation symptoms, to assess the different effect between two groups. Resuh： The treatment group based on stool frequency of a week, scores of constipation symptoms had significant differences compared before and after treatment （ P〈0.01 ）. For the control group, the score of difficult defecation of had no statistically differences （P〉0.05）, the score of tenesmus had statistically differences （ P〈0.05 ）, and other scores of constipation symptoms had significant differences compared before and after treatment （P〈0.01）. At the end of the treatment, two groups had statistically differences of stool frequency （ P〈0.05 ）, and significant differences in stool frequency, difficult defecation, abdominal distension （ P〈0.01 ）, but no statistically differences in total score, stool property, defecation time, and tenesmus （ P〉0.05 ）. Conclusion ： Acupuncture at acupoints of ST25 matching ST37 and unspecific＇ points are both effective in the treatment of FC patients. But the efficacy of acupuncture at ST25 matching ST37 in improving the symptoms of FC patients are superior to those of unspecific acupuncture.