中老年人群体脂分布与脉搏波传导速度之间的关系

Relationship between body fat distribution and pulse wave velocity in middle-aged and aged population

目的:探讨中老年人群体脂分布与脉搏波传导速度(PWV)之间的关系。方法:选取200例于我院进行健康检查的中老年人,分成男子组(103例)和女子组(97例)。所有个体测量内脏脂肪量(VFV)、皮下脂肪量(SFV)、臂踝脉搏波传导速度(ba-PWV)。结果:男子组VFV高于女子组[(3.17±0.84)kg vs.(2.30±0.94)kg],SFV低于女子组[(15.56±3.49)kg vs.(17.69±4.82)kg]。男子组ba-PWV与年龄、VFV、空腹血糖、SBP、及DBP呈正相关;女子组ba-PWV与年龄、SFV、TG、BUN、SBP及DBP呈正相关,而与HDL-C、Apo A1呈负相关。结论 :中老年健康人群体脂分布存在性别差异,男子组年龄、VFV、SBP及DBP是影响ba-PWV大小的独立危险因素;女子组年龄、SBP及Apo A1是影响ba-PWV大小的独立危险因素。

Objective To investigate the relationship between body fat distribution and pulse wave velocity （PWV） in middle-aged and aged population. Methods Two hundred patients received health examination were enrolled into the male group （103 cases） and the female group （97 cases）. Visceral fat volume （VFV）, subcutaneous fat volume （SFV） and ba-PWV were determined. Results Compared to patients in the female group, patients in the male group had significantly higher VFV values [（3.17 ± 0.84） kg vs （2.30 ± 0.94） kg], and lower SFV values [（15.56± 3.49） kg vs （17.69 ± 4.82） kg], In the male group, there existed a positive correlation between ba-PWV and age, VFV, fasting blood glucose, SBP and DBP. In the female group, a positive correlation was found between ba-PWV and age, SFV, TG, BUN, SBP and DBP, while a negative correlation was observed for HDL-C and Apo A1. Conclusion There was gender differences in body fat distribution in middle-aged and aged healthy population. In the male group, age, VFV, SBP, and DBP were the only independent and significant risk factors for ba-PWV. In the female group, age, SBP and Apo A1 were the independent risk factors for ba-PWV.