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声辐射力脉冲成像技术评价胆道闭锁肝脏纤维化 被引量:3

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摘要 目的:探讨声辐射力脉冲成像技术(ARFI)无创评价胆道闭锁肝纤维化的价值。方法:回顾性分析2013年6月至2014年5月我院外科手术治疗的30例胆道闭锁患儿术中肝脏病理及术前肝脏ARFI检查结果。ARFI检查结果以肝右叶平均剪切波速度(Vs)表示。对患儿肝组织病理进行肝纤维分期。将Vs与病理结果做比较。结果:对30例胆道闭锁术患儿的肝脏病理进行分级。S0~S4期的胆道闭锁患儿分别为0、4、10、11和5例。根据肝脏病理分级本研究组分为4组,即S1、S2、S3、s4组,其相应的平均速度Vs分别为(1.48±0.11)、(1.84±0.11)、(2.20±0.24)及(3.12±0.25)m/s,各组间差异均有显著统计学意义(P〈0.001)。进一步行组内Vs均值两两比较,vs在S1与S2组间差异存在统计学意义(P〈0.05),S1与S3、S1与S4、S2与S3、S2与S4及S3与S4组间差异有显著统计学意义(P〈0.001)。vs与肝纤维化分期之间有很好的相关性(r=0.941,P〈0.001)。结论:声辐射力脉冲成像技术可作为评价胆道闭锁患儿肝纤维化程度的有效手段。
出处 《实用医学杂志》 CAS 北大核心 2015年第16期2725-2727,共3页 The Journal of Practical Medicine
基金 广州市卫生局医药卫生科技项目(编号:2014A010023)
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