摘要
目的探讨结直肠癌(colorectal cancer,CRC)肺转移手术治疗后的生存预后情况。方法回顾性分析复旦大学附属中山医院胸外科2008年1月至2013年12月期间30例CRC肺转移手术治疗患者的临床资料。分析CRC原发灶手术与肺转移灶手术间期(disease-free interval,DFI)、癌胚抗原(carcinoembryonic antigen,CEA)、肺转移灶个数对术后生存情况的影响。结果高水平CEA是患者预后不良的因素,而DFI与CRC肺转移的病灶个数等对患者术后生存时间影响相对较小。结论积极手术治疗CRC肺转移可取得良好的预后疗效。
Objective To investigate the survival prognosis after the surgery of pulmonary metastasis from colorectal cancer （CRC）. Methods Clinical data of 30 cases with postoperative pathologically proven pulmonary metastasis from CRC in Zhongshan Hospital, Fudan University between Jan. , 2008 and Dec. , 2013 were analyzed retrospectively. We evaluated the influences of disease-free interval （DFI） of CRC primary lesions surgery and pulmonary metastasis surgery, carcinoembryonic antigen （CEA） and the number of pulmonary metastasis on survival and prognosis. Results High level of CEA was an important factor for Poor prognosis. DFI and the number of pulmonary metastasis were not significantly correlated with the patients＇ survival. Conclusions Active surgery treatment for pulmonary metastasis from CRC do generate good prognosis.
出处
《复旦学报（医学版）》
CAS
CSCD
北大核心
2015年第4期524-527,共4页
Fudan University Journal of Medical Sciences
基金
国家自然科学基金(81401875
81472225)
上海市自然科学基金(14ZR14060000)~~
关键词
结直肠癌
肺转移
癌胚抗原
colorectal cancer
pulmonary metastasis
carcinoembryonic antigen
