慢性阻塞性肺疾病急性加重期患者合并抑郁调查分析

An investigation and analysis of patients with acute exacerbations of chronic obstructive pulmonary disease and depression

目的:研究慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)患者抑郁发生情况及其相关因素分析。方法:入院3 d内95例患者均使用抑郁自评量表进行测评,并根据测评结果将患者分为观察组(合并抑郁患者)和对照组(无抑郁患者),对两组数据进行分析、对比。结果:观察组52例,对照组43例,抑郁症发生率54.7%(52/95),两组患者在年龄、病程、吸烟指数、1秒钟用力呼气容积、用力肺活量、动脉血氧分压、动脉血二氧化碳分压及住院天数等方面对比,差异均有统计学意义(P<0.01)。观察组轻度抑郁27例(51.9%),中度抑郁23例(44.2%),重度抑郁2例(3.8%)。结论:AECOPD患者合并抑郁症发病率较高,病情严重者更易发生,临床医护人员应重视抑郁症,积极治疗,以改善患者的生活质量及预后。

Objective：To study depression incidence and its associated factors in patients acute exacerbation of chronic obstruc-tive pulmonary disease（AECOPD）. Methods：95 patients within 3 days after admission using self rating depression scale（SDS）were measured and were divided into the observation group（ depression） and control group（ no depression） according to the evaluation results. The data were compared and analysed between two group. Results：52 cases were in the observation group,43 cases in the control group and the incidence of depression was 54. 7%（52/95）. Age,course of disease,smoking index,forced expiratory volume in one second, forced vital capacity, PaO2 , PaCO2 and hospitalization days and comparison had significant differences between the two groups （P〈0. 01）. 27 cases were mild depression（51. 9%）,23 patients with moderate depression（44. 2%）and severe depression in 2 cases （3. 8%）in the observation group. Conclusion：AECOPD patients have a higher incidence of depression,in particular,severe cases were more susceptible,Clinicians should pay attention to depression,aggressively treat to improve quality of life and prognosis.