摘要
AIM: To evaluate the determination of the margin of differentiated-type early gastric cancers by using conventional endoscopy.METHODS: We retrospectively evaluated 364 differentiated early gastric cancers that were endoscopically resected as en-bloc specimens and diagnosed pathologically in detail between November 2007 and October 2008. All procedures were done with conventional endoscopes and all endoscopic samples, before and after indigo carmine dye, were re-evaluated using a digital filing system by one endoscopist. We analyzed the incidence of lesions with unclear margins and the relationship between unclear margins and relevant clinicopathological findings. RESULTS: The rate of lesions with unclear margins was 20.6%(75/364). Multivariate regression analysis suggested that the factors that make the determination of the margin difficult were normal color, presence of components of flat area(0-IIb), a diameter ≥ 21 mm, ulceration, and components of poorly differentiated adenocarcinoma in the mucosal surface.CONCLUSION: As many as 20% of differentiated early gastric cancers show unclear margins. Consideration of the factors associated with unclear margins may help endoscopists to accurately determine the margins of the lesion.
AIM To evaluate the determination of the marginof differentiated-type early gastric cancers by usingconventional endoscopy.METHODS： We retrospectively evaluated 364 differentiatedearly gastric cancers that were endoscopicallyresected as en-bloc specimens and diagnosed pathologicallyin detail between November 2007 and October2008. All procedures were done with conventionalendoscopes and all endoscopic samples, before and afterindigo carmine dye, were re-evaluated using a digital filingsystem by one endoscopist. We analyzed the incidence oflesions with unclear margins and the relationship betweenunclear margins and relevant clinicopathological findings.RESULTS： The rate of lesions with unclear marginswas 20.6% （75/364）. Multivariate regression analysissuggested that the factors that make the determinationof the margin difficult were normal color, presence ofcomponents of flat area （0-IIb）, a diameter ≥ 21 mm,ulceration, and components of poorly differentiatedadenocarcinoma in the mucosal surface.CONCLUSION： As many as 20% of differentiated earlygastric cancers show unclear margins. Consideration ofthe factors associated with unclear margins may helpendoscopists to accurately determine the margins of thelesion.
