整形外科抗菌药物管理前后手术感染率的统计分析

Statistical analysis of infection rate before and after administration of antibiotics in plastic surgery

目的分析对比抗菌药物管理前后医院整形外科手术感染率,探讨抗菌药物管理对控制整形外科手术感染的重要性,为临床治疗提供参考依据。方法回顾性分析2010年8月-2012年8月在医院整形外科手术的1550例患者临床资料,根据患者是否进行抗菌药物管理将其分为抗菌药物管理组(2011年8月-2012年8月)850例和抗菌药物未管理组(2010年8月-2011年8月),分析两组患者抗菌药物使用情况与手术感染率。结果抗菌药物管理组Ⅱ类和Ⅲ类手术患者抗菌药物使用率显著高于Ⅰ类手术患者,差异有统计学意义(P<0.05);抗菌药物管理组I类手术患者抗菌药物使用率显著低于抗菌药物未管理组Ⅰ类手术患者,差异有统计学意义(P<0.05);抗菌药物未管理组700例患者中,11例患者发生切口感染,感染率为1.57%;抗菌药物管理组850例患者中,5例患者发生感染,感染率为0.59%,抗菌药物管理组患者感染的发生率显著低于抗菌药物未管理组,差异具有统计学意义(P<0.05)。结论在整形外科手术中,规范性使用抗菌药物可以减少外科手术中抗菌药物滥用的现象,可降低整形外科手术感染率,值得广泛推广。

OBJECTIVE To analyze the infection rate in plastic surgery after adopting antibiotic administration so as to investigate the importance of antibiotic management in the control of infections during orthopedic surgeries . METHODS From Jan .2012 to Apr .2013 ,the clinical data of 1550 cases who adopted plastic surgeries in our hos‐pital were retrospectively analyzed .They were divided into two groups according to whether given antibiotics ad‐ministration ,namely antibiotics management group （from Aug .2011 to Aug .2012） with 850 cases and antibiotics unmanaged using group （from Aug .2010 to Aug .2011） with 700 cases .The antibiotic using condition and opera‐tion infection rate were compared between the two groups .RESULTS The type Ⅱ and type Ⅲ patients in the anti‐biotic management group used more antibiotics than the type Ⅰ patients and the differences were significant （P＆lt;0 .05） .And type Ⅰ patients had an obviously lower antibiotic use rate than that of the type Ⅰ patients in the un‐managed group and the differences were significant （P〈0 .05） .In the 700 cases of patients in the unmanaged group ,11 patients got infected and the infection rate was 1 .57% ;while in the 850 cases of patients in the manage‐ment group ,5 patients were found to be infected ,and the infection rate was 0 .59% .Patients in the antibiotic management group had a significant lower infection occurrence rate than the antibiotic unmanaged using group and the differences were significant （P〈0 .05） .CONCLUSION The use of antibiotics in a standardized way can reduce the unreasonable phenomenon during plastic surgeries and can prevent the abuse of antibiotics hence is worthy to be promoted .