代谢综合征中医辨证分型与尿微量白蛋白及颈动脉内膜中层厚度关系

Correlation between Syndrome Differentiation and Treatment Uariation of Metabolic Syndrome and Urine Trace Albumin and Intima Media Thickness

目的:探讨代谢综合征(MS)患者不同中医证型的尿微量白蛋白及颈动脉内膜中层厚度的关系,为中医辨证论治提供一定的客观依据。方法:选择MS患者80例,根据中医证候分为痰瘀互结型,气滞湿阻型,脾肾气虚型和气阴两虚型。对患者的一般资料、尿微量白蛋白检测结果及颈动脉内膜中层厚度进行比较。结果:MS痰瘀互结型患者的MAU高于气滞湿阻型及脾肾气虚型(P<0.05);MS痰瘀互结型患者的IMT大于气滞湿阻型(P<0.01),大于脾肾气虚型及气阴两虚型(P<0.05)。结论:痰瘀互结型的MS患者更应注意肾脏及血管并发症的防治,尿微量白蛋白及颈动脉内膜中层厚度可以作为MS患者中医辨证分型的参考。

Objective：To explore the relationship between the urine trace albumin and intima media thickness among Met-abolic Syndrome （ MS） patients with different traditional Chinese medicine（ TCM） syndromes, and to provide some ob-jective basis for syndrome differentiation and treatment variation.Methods：Eighty patients were enrolled and assigned to inter-stagnation phlegm and blood stasis type, Qi stagnation and dampness obstruction type, Qi asthenia of the spleen and kidney type, asthenia of Qi and Yin type according to TCM syndrome.Ccompare the general information,the urine trace albumin and intima media thickness among them.Results：MAU of MS patients with inter-stagnation phlegm and blood stasis type was higher than Qi stagnation and dampness obstruction type and Qi asthenia of the spleen and kidney type （ P＆lt;0.05 ）; IMT of MS patients with inter-stagnation phlegm and blood stasis type was much greater than Qi stagnation and dampness obstruction type （P＆lt;0.01）, and was also greater than Qi asthenia of the spleen and kidney type and asthenia of Qi and Yin type （P＆lt;0.05）.Conclusion：MS patients with inter-stagnation phlegm and blood sta-sis type shouldpay more attention to the prevention and treatment of renal and vascular complications,and urine trace al-bumin and intima media thickness can be a reference of traditional Chinese medicine in patients with MS.