愈创木烷型倍半萜类天然产物及其类似物的全合成研究进展

Progresses in Total Synthesis of Guaiane Sesquiterpenes and Their Analogues

综述了愈创木烷型倍半萜类天然产物及其类似物的全合成研究进展.主要包括以卡宾羰基叶立德环化串联反应、烯烃复分解环化反应、分子内羟醛缩合反应等作为关键反应的方法来构筑该类天然产物的基本骨架.

The recent progresses in the total synthesis of guaiane sesquiterpenes and their analogues are reviewed, which include the carbene cyclization-cycloaddition cascade reaction, olefin ring closing metathesis reaction, intramolecular aldol reaction as the key steps to construct basic ring system of these natural products.