期刊文献+

甲状腺结节细针穿刺细胞学检查的诊断价值 被引量:8

Clinic value of fine needle aspiration cytology in the diagnosis of thyroid nodule
下载PDF
导出
摘要 目的分析甲状腺结节细针穿刺细胞学检查(fine-needle aspiration biopsy,FNAB)的应用价值。方法回顾性分析578例行FNAB检查患者的临床病理资料。应用Bethesda报告系统诊断分类,对其中手术治疗的132例患者的组织病理与细胞病理进行对照。结果 132例患者的FNAB检查结果应用Bethesda报告系统诊断分类,将标本分为6类,分别是:标本无法诊断占7.6%;良性病变占43.2%;意义不明确的细胞非典型病变占19.7%;滤泡性肿瘤及可疑滤泡性肿瘤占5.3%;可疑恶性肿瘤占6.8%;恶性肿瘤占17.4%。将FNAB检查结果与组织病理对照后发现:甲状腺结节细针穿刺判断甲状腺良恶性结节的灵敏度及特异度分别为81.1%和97.6%,阳性预测值为93.8%。结论甲状腺细针穿刺对于鉴别甲状腺良恶性结节是可靠的方法。 Objective To study the clinical value of fine-needle aspiration cytology of thyroid nodule. Methods A retrospective review was performed among 578 consecutive cases of FNA cytology of thyroid nodules. Cytologic diagnoses were classified as non-diagnostic or unsatisfactory, benign, atypia of unknown significance/follicular lesion of unknown significance(AUS/FLUS) , suspicious for follicular neoplasm(SFN) , suspicious for malignancy and malignancy based on the Bethesda system. The discrepancies between initial cytologic diagnoses and histologic diagnoses were evaluated among 132 surgical specimens. Results Among 132 cases who underwent surgery, FNAs were 7.6% unsatisfactory, 43.2% benign, 19.7% AUS/FLUS, 5.3% SFN, 6.8% suspicious, and 17.4% malignant. The sensitivity, specificity and positive predictive value of thyroid FNA for the diagnosis of malignancy were 81.1% ,97.6% and 93.8% respectively. Conclusions Fine-needle aspiration is a reliable method for identifying benign and malignant thyroid nodules.
出处 《中国肿瘤外科杂志》 CAS 2015年第4期235-237,252,共4页 Chinese Journal of Surgical Oncology
关键词 甲状腺结节 细针穿刺细胞学检查 诊断 thyroid nodule fine-needle aspiration biopsy diagnosis
  • 引文网络
  • 相关文献

参考文献9

  • 1Ali SZ, Cibas ES. The bethesda system for reporting thyroid cytopa- thology : Definitions, criteria and explanatory notes [ M ]. New York : Springer,2010 : 1-165.
  • 2Cooper DS, Doherty GM, Haugen BR, et al. Revised American Thyroid Association management guidelines for patients with thy- roid nodules and differentiated thyroid cancer [ J ]. Thyroid, 2009, 19(11) :1167-1214.
  • 3Orell S, Sterret G, Whitaker D, et al. Thyroid [ M ]. UK: Elsevier Churchill Livingstone ,2005 : 125-164.
  • 4Lewis CM, Chang KP, Pitman M, et al. Thyroid fine-needle aspi- ration biopsy : variability in reporting [ J ]. Thyroid, 2009,19 ( 7 ) : 717-723.
  • 5中国甲状腺疾病诊治指南——甲状腺结节[J].中华内科杂志,2008,47(10):867-868. 被引量:293
  • 6Gharib H, Papini E, Paschke R, et al. American association of clinical Endocrinologists, associazione medici endocrinologi, and European thyroid association medical guidelines for clinical prac- tice for the diagnosis and management of thyroid nodules[ J]. En- docr Pract,2010,16 ( suppl 1 ) : 1-43.
  • 7Theohafis CGA, Sehofield KM, Hammers L, et al. The Bethesda thyroid fine-needle aspiration classification system: year 1 at anacademic institution [ J ]. Thyroid,2009,19 ( 11 ) : 1215-1223.
  • 8Cibas ES, Dueatman BS. Thyroid [ M ]. Philadelphia : Saunders, 2009:255-284.
  • 9Robitsehek J, Straub M, Wirtz E, et al. Diagnostic efficacy of surgeon-performed ultrasound-guided fine needle aspiration: a randomized controlled trial [ J ]. Otolaryngol Head Neck Surg, 2010,142(3) : 306-309.

二级参考文献6

  • 1Gharib H, Papini E. Thyroid nodules: clinical importance, assessment, and treatment. Endocrinol Metab Clin North Am, 2007, 36:707-735.
  • 2AACE/AME Task Force Thyroid Nodules. American Association of Clinical Endocrinologists and Associazione Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nedules. Endocr Pract, 2006,12:63-102.
  • 3Filetti S, Durante C, Torlontano M. Nonsurgical approaches to the management of thyroid nodules. Nat Clin Praet Endoerinol Metab, 2006, 2:384-394.
  • 4Abalovich M, Amino N, Barbour LA, et al. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab, 2007, 92 :S1-47.
  • 5Cooper DS, Doherty GM, Haugen BR, et al. Management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid, 2006, 16: 109-142.
  • 6连小兰.甲状腺结节.见:白耀,主编.甲状腺病学[M].北京:科学技术文献出版社,2004.335-336.

共引文献292

同被引文献55

引证文献8

二级引证文献59

;
使用帮助 返回顶部