噻托溴铵联合沙美特罗治疗重症支气管哮喘的临床疗效

Clinical efficacy of Tiotropium combined with Salmeterol for severe bronchial asthma

目的研究噻托溴铵联合沙美特罗治疗重症支气管哮喘患者的临床疗效。方法回顾性分析我院在2009年1月～2013年2月间收治的60例重症支气管哮喘患者的临床资料,根据治疗方法分为两组,每组各30例病例。观察组采用噻托溴铵联合沙美特罗治疗,对照组采用沙美特罗治疗,比较两组患者的临床疗效。结果观察组治疗总有效率、不良反应均优于对照组,差异具有统计学意义（P〈0.01）。结论噻托溴铵联合沙美特罗在支气管重症哮喘的治疗中疗效确切,值得临床推广。

Objective To discuss clinical efficacy of Tiotropium combined with Salmeterol for severe bronchial asthma. Methods Clinical data of 60 cases with severe bronchial asthma from Jan 2009 to Feb 2013 were retrospectively analyzed, and all patients were divided into two groups according to the treatment, each group with 30 cases. Observer group was treated by Tiotropium combined with Salmeterol, and control group was treated by Salmeterol. Clinical efficacy was compared between two groups. Results Total efficiency of observer group was higher than control group, and adverse reactions of observer group was lower than control group（P 〈 0.01）. Conclusion Tiotropium combined with Salmeterol for severe bronchial asthma shows curative effect, worthy of clinical promotion.