生长抑素联合垂体后叶素治疗肝硬化上消化道出血的疗效观察

Efficacy of somatostatin combined with vasopressin for treating cirrhosis combined upper gastrointestinal bleeding

目的探讨生长抑素联合垂体后叶素对肝硬化合并上消化道出血的疗效。方法选取2012年1月～2014年1月在我院就诊的42例肝硬化合并上消化道出血的患者随机分为对照组（20例）及观察组（22例）。对照组给予垂体后叶素持续静脉滴注,观察组予以生长抑素＋垂体后叶素持续静脉滴注治疗,观察并比较两组的临床疗效。结果对照组总有效率为70.0%,观察组总有效率为90.9%,两组比较差异具有统计学意义（P〈0.05）。结论生长抑素联合垂体后叶素治疗肝硬化合并上消化道出血疗效显著。

Objective To investigate the efficacy of somatostatin combined with vasopressin for treating cirrhosis combined upper gastrointestinal bleeding. Methods Selected 42 cases of cirrhosis with gastrointestinal bleeding from January 2012 to January 2014 in on our hospital, All cases were randomLy divided into control group （20 cases） and the observation group （22 cases）. The control group were given continuous intravenous infusion of vasopressin, and the observation group were added the intravenous somatostatin ＋ vasopressin infusion therapy, observe and compare the clinical efficacy of the two groups. Results The total effective rate was 70.0% in the control group, so that was 90.9%in the treatment group, the difference compared between the two groups was statistically significant （P〈0.05）. Conclusion The combined pituitary hormone somatostatin treatment of upper gastrointestinal bleeding with cirrhosis has significant effect.