多病种间短程心率变异性观察

Observation of short-time heart rate variability in patients' ECG with different diseases

目的观察冠心病、高血压、艾滋病、肺结核、病毒性肝炎之间及各病种与正常人短程心率变异性的不同,探讨短程心率变异性的可靠性及临床意义。方法将135例患有冠心病、高血压、艾滋病、肺结核、病毒性肝炎的住院患者和90例正常人的短程心率变异性指标作对比分析,寻找不同病种组间差异。结果艾滋病短程心率变异性较正常人显著降低[RR间期标准差:(14.3±14.4)vs(27.5±8.2),P<0.05;变异系数:(2.11±1.3)vs(3.55±1.4),P<0.05];高血压、冠心病组RR间期标准差,变异系数较正常组降低,但差异无统计学差异;肺结核,病毒性肝炎组与正常组比较无显著变化。结论与其他疾病相比,艾滋病引起心率变异性下降程度更大,肺结核、病毒性肝炎心率变异性最接近正常。

Objective To explore reliability of short-time heart rate variability （HRV） and clinical significance by observing the difference between coronary heart disease,hypertension,acquired immune deficiency syndrome （AIDS）,tuberculosis,viral hepatitis and other diseases and short-time HRV of healthy people. Methods 135 hospitalized patients with coronary heart disease,hypertension,AIDS,tuberculosis,viral hepatitis and 90 healthy people＇s short-time HRV were compared and analyzed to find differences between different diseases. Results Short-time HRV of patients with AIDS was significantly decreased compared with that of healthy people [Standard deviation of the RR interphase：（14.3±14.4）vs（27.5±8.2）,P〈0.05;Coefficient of variation（2.11±1.3）vs（3.55±1.4）,P〈0.05]. Standard deviation and coefficient of variation of RR interphase in hypertension group and coronary heart disease group were decreased compared with those in normal group,but the differences were not statistically significant.There was not significant change in tuberculosis group and viral hepatitis group compared with normal group. Conclusion AIDS can cause greater decrease in short-time heart rate variability compared with other diseases,and that of patients with tuberculosis and viral hepatitis are the closest to normal level.