营养支持辅助晚期恶性肿瘤化疗体会

Experience on auxiliary nutritional support in chemotherapy of advanced malignant tumor

目的探讨营养支持辅助晚期恶性肿瘤化疗结果。方法将我院2010年8月~2013年8月所医治晚期恶性肿瘤化疗患者80例作为研究对象,按其方法分成两组,每组40例,对照组患者进行常规化疗,观察组患者在常规化疗的基础上进行营养支持,观察、比较两组患者的化疗结果。结果观察组患者化疗后白蛋白（ALB）和氮平衡指标下降程度明显低于对照组,免疫球蛋白A（Ig A）、免疫球蛋白G（Ig G）、免疫球蛋白M（Ig M）优于对照组,且化疗过程中不良反应发生率低于对照组,差异具有统计学意义（P〈0.05）。结论晚期恶性肿瘤患者化疗过程中配合营养支持,能减少患者免疫功能的进一步恶化,改善患者生活质量,值得推广使用。

Objective To study the results of chemotherapy of auxiliary nutritional support in advanced malignant tumor. Methods 80 patients with advanced malignant tumor, who were treated with chemotherapy in our hospital from August 2010 to August 2013, were selected as the research objects and were divided into two groups according to the treatment methods, with 40 cases in each group. To observe and compare the results of chemotherapy between control group who were treated with conventional chemotherapy and observation group who were treated with auxiliary nutritional support based on conventional chemotherapy. Results The decreasing degree of Albumin（ALB）and nitrogen balance in observation group were obviously lower than which in control group, Immunoglobulin A（IgA）, Immunoglobulin G（IgG）, and Immunoglobulin M（IgM）in observation group were better than which in control group, furthermore, the incidence of adverse reactions in the course of chemotherapy in observation group were lower than which in control group, the differences were statically significant（P 〈 0.05）. Conclusion Auxiliary nutritional support in chemotherapy of advanced malignant tumor could reduce further deterioration of patients＇immune function, could improve then quality of life, is worthy of clinical popularization and application.