2型糖尿病患者血清超敏C反应蛋白与糖尿病肾病相关性分析

The relationship between high sensitivity C reactive protein and diabetic nephropathy in patients with type 2 diabetes mellitus

目的：探讨2型糖尿病患者血清超敏 C 反应蛋白与糖尿病肾病相关性。方法随机选取2013年5月～2014年5月我院就诊的糖尿病患者75例，将患者根据糖尿病肾病分期标准分为单纯糖尿病组（45例）及糖尿病肾损害组（30例）。选取同期体检的无糖尿病患者50例作为对照组。对三组患者的 hs-CRP， FPG、TG、尿微量白蛋白（MALB）、hs-CRP、HbA1c、Cr 水平进行比较。结果各组之间，随着糖尿病肾损害增加，FPG、TG、尿微量白蛋白、hs-CRP、HbA1c、Cr 水平逐渐增高，与对照组比较差异有统计学意义（P ＜0.05）。糖尿病肾病患者 hs-CRP 与 TG，FPG，HbA1C，Cr 及 MALB 呈正相关。结论血清超敏 C 反应蛋白与2型糖尿病患者肾损害程度一致。

Objective To explore the relationship between high sensitivity C reactive protein and diabetic nephropathy in patients with type 2 diabetes mellitus. Methods 75 diabetic patients were randomly selected in 2013 May to 2014 year in May in our hospital for treatment of patients,patients will be according to the different stages of diabetic nephropathy standards are divided intosimple diabetes group（45 cases）and diabetic renal damage group（30 cases）.Select the year examination of the patients without diabetes and 50 patients as control group.The three groups of patients with hs-CRP,compared FPG,TG,urinary albumin,hs-CRP,HbA1c,Cr level.Were all observed. Results Between the groups,with diabetic renal damage increased,FPG,TG,MALB,hs-CRP,HbA1c,Cr levels gradually increased,a significant difference compared with the control group（P 〈 0.05）.Diabetic nephropathy in patients with hs-CRP and TG,FPG,HbA1C,Cr and MALB were positively correlated . Conclusion Serum high sensitivity C reactive protein and type 2 diabetic patients with renal damage degree of consistency.