酪蛋白磷酸多肽-无定形磷酸钙对固定正畸所致牙釉质脱矿的影响

The Influence of Casein Phospho Peptides-Amorphous Calcium Phosphate on Enamel Demineralization Induced by Fixed Orthodontic

目的:研究酪蛋白磷酸多肽-无定形磷酸钙(商品名GC护牙素)对固定正畸所致牙釉质脱矿的影响。方法:选择固定正畸治疗患者40例,经签字同意进入实验。以随机数字表法随机分为对照组、实验组各20例。对照组在口腔卫生宣教的基础上采用单纯口腔卫生措施,实验组在对照组的基础上使用GC护牙素。2组患者从治疗开始,进行连续13个月的牙照片观察。观测指标为牙面是否有新出现的的白垩色斑片或龋洞,统计并计算牙釉质脱矿率及脱矿指数(EDI)。结果:(1)对照组、实验组的牙釉质脱矿率均随着时间的增加而增高;(2)对照组EDI高于实验组。结论:在口腔卫生措施的基础上使用GC护牙素预防固定正畸所致牙釉质脱矿是一种安全有效的措施。

Objective： To study the influence of casein phospho peptides - amorphous calcium phosphate （ Casein phosphopeptide - amorphic calcium phosphate, CPP- ACP, the product name of GC Tooth Mousse） on enamel demineralization as fixed orthodontic. Methods ：40 patients with fixed orthodontic treatment were randomly divided into a control group A group and experimental group B, each group of 20. GroupA had a simple oral hygiene measure on the basis of health education, group B had GC Tooth Mousse on the basis ofgroup A. From the start of treatment to 13 -month, observed teeth photograph on two groups, observed whether there were emergine piece of chalk stain or cavities on teeth surface. Analysed by statistics and calculated the rate of enamel demineralization and demineralization Index（EDI）. Results：（ 1 ）The enamel demineralization rate was increases in both group A and group B with time passing; （ 2 ） EDI of group A was higher than that in group B, there was a statistically significant. Conclusion：The use of CPP- ACP of containing GC Tooth Mousse on the basis of oral hygiene measures in preventing enamel demineralization are safe and effective measure.