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TCT、HPV-DNA及阴道镜检查在宫颈病变中的意义 被引量:7

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摘要 目的:探讨宫颈液基细胞学检查(TCT)、人乳头瘤病毒基因(HPV-DNA)检测联合阴道镜检查在宫颈病变中的诊断价值。方法:选取1 240名在我院进行宫颈筛查的有性生活妇女,对其进行TCT、HPV-DNA检测,对于未能明确意义的不典型鳞状细胞(ASC-US)以上的92例患者、HPV-DNA检测阳性的284例中的62例高危型患者进行阴道镜下多点活检。结果:TCT检查阳性92例(7.42%);HPV-DNA检测阳性284例(22.90%),HPV-DNA检测阳性率明显高于TCT(P<0.05)。92例TCT阳性的患者宫颈活检结果:慢性宫颈炎61例、CINⅠ6例、CINⅡ9例、CINⅢ14例、SCC2例;62例高危型HPV感染患者活检结果:慢性宫颈炎16例、CINⅠ19例、CINⅡ15例、CINⅢ9例、SCC 3例。结论:TCT、高危型HPV-DNA及阴道镜检查可明显提高CIN阳性检出率,是进行宫颈病变筛查的重要方法,只有联合应用,才能更早地发现宫颈癌前病变,预防宫颈癌的发生。
出处 《现代临床医学》 2015年第4期276-277,279,共3页 Journal of Modern Clinical Medicine
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