摘要
目的:探讨青年结肠癌患者术后肝转移的危险因素。方法收集2002年1月~2012年12月来源于成都市第五人民医院行结肠癌根治术的青年结肠癌患者共527例,并收集其临床病理资料。采用多因素Logistic回归方法分析影响青年结肠癌患者术后发生肝转移的因素。结果527例青年结肠癌患者中术后肝转移的发生率为21.3%。同时,肿瘤较大者(跃5 cm)会增加青年结肠癌患者术后肝转移的发生风险(OR =5.57,95%CI院2.25~13.76);脉管侵犯者也会增加青年结肠癌患者术后肝转移的发生风险(OR =3.16,95%CI院1.60~6.21);淋巴结转移是青年结肠癌患者术后发生肝转移的独立危险因素(OR =5.25,95%CI院2.99~9.19)。结论肿瘤大小、脉管侵犯、淋巴结转移是影响青年结肠癌患者术后发生肝转移的主要因素,提示青年结肠癌患者发生术后肝转移与肿瘤的病理学特征存在着较为密切的关系。
Objective To explore the risk factors of postoperative liver metastasis in young patients with colon cancer. Methods A total of 527 patients who had been conducted colorectal surgery in Chengdu Fifth People's Hospital from January 2002 to December 2012 were collected. And the clinical pathological data was collected. Multinomial Logistic regression was used to analyze the risk factors of postoperative liver metastasis in young patients with colon cancer. Results The incidence of liver metastasis after colorectal surgery of young patients with colon cancer in the 527 pa-tients was 21.3%. Simultaneously, larger tumor size with more than 5 centimeter increased the risk of liver metastasis after colorectal surgery in young patients with colon cancer (OR = 5.57, 95%CI: 2.25-13.76). Vascular invasion in-creased the risk of liver metastasis after colorectal surgery in young patients with colon cancer (OR = 3.16, 95%CI:1.60-6.21). Lymph node metastasis was the independent risk factor of liver metastasis after colorectal surgery in young patients with colon cancer (OR = 5.25, 95%CI: 2.99-9.19). Conclusion Tumor size, vascular invasion, lymph node metastasis are the main factors which influence the young patients with liver metastasis of colon cancer, which reminds that the risk of liver metastasis after colorectal surgery in young patients with colon cancer is closely related to the pathological characteristics.
出处
《中国医药导报》
CAS
2015年第24期26-29,共4页
China Medical Herald
关键词
青年
结肠癌
肝转移
危险因素
Young
Colon cancer
Liver metastasis
Risk factor