贵州某高校新生幽门螺杆菌感染的流行病学调查

A research into the epidemiology of Helicobacter pylori infection in freshmen from a college of Guizhou Province

目的了解高校新生幽门螺杆菌(Hp)感染情况,更好地实施针对新生Hp感染的干预措施。方法采用ELISA法对某高校583名新生进行人血清Hp-Ig G抗体检测感染相关因素调查,用SPSS软件进行统计分析。结果贵州某高校583例新生Hp感染率为45.45%,高中就餐(不同场所)、饮水(生水/开水)、共饮水(是/否)、餐具(自用/公用)、吃大蒜(吃/不吃)及家人胃病(有/无)组内比较有统计学意义(P均<0.05)。二分类logistic回归分析中,Hp感染相关危险因素:家人患胃病(OR=0.262);餐具(OR=0.519);大蒜(OR=0.666);共饮水(OR=1.469);接吻(OR=1.710)。结论贵州某高校新生Hp感染低于全国平均水平,其感染危险因素与家人患胃病、"口-口"传播及生活习惯有关。

Objective To understand the infections of helicobacter pylori （Hp） in treshman lrom a college ot Guizhou Province and take some appropriate intervening measures. Methods We checked Hp-IgG antibodies and the related risky factors of Hp infections in 583 freshmen by means of ELISA and questionnaire method. SPSS software was used for statistical analysis and comparison on different levels. Results The total Hp infection rate was 45.45%. The infection rate showed a significant difference in the freshmen from different dining places in senior high schools,there were also significant diferences in the freshmen from sharing drinking water and not sharing, drinking boiled water and not boiled, having kissing events and having not, sharing tableware and not sharing, eating garlic and not eating, as well as the family members with gastric diseases and without （all P values were less than 0.05）. In logistic regression analysis, the related risk factors of Hp infection included family members suffering from gastric diseases （OR=0.262）, sharing tableware （ OR=O. 519） ,eating garlic （OR=0.666） ; sharing drinking water （OR=l.469）,having kissing events （OR=l.710）. Conclusion The Hp infection rate of freshmen in the college is lower than that of the national average. The infection risk factors are related to family＇ s members suffering from gastric diseases, mouth to mouth transmission as well as living habits.