摘要
目的:探讨宫颈腺癌卵巢转移的发生率及危险因素。方法:回顾分析1990年1月至2012年8月在浙江省肿瘤医院行手术治疗的321例宫颈腺癌的临床病理资料,所有患者均切除双侧附件。分析患者的临床病理特点,探讨宫颈腺癌卵巢转移的高危因素。结果:16例患者出现卵巢转移(4.98%),中位年龄52±13岁。单因素分析显示,子宫体受累、淋巴结转移、浸润深度大于1/2、期别大于ⅠB期、宫旁侵犯是卵巢转移的高危因素。多因素分析显示,宫旁侵犯是唯一的独立高危因素。16例患者的2年及5年生存率分别为81.3%和62.5%。结论:宫颈腺癌卵巢转移的发生率高于宫颈鳞癌,对于有高危因素的患者,保留卵巢需慎重。
Objective:To investigate the incidence and the risk factors of ovarian me- tastasis in patients with cervical adenocarcinoma. Methods :321 patients with cervical adenocar- cinoma were treated at Zhejiang Cancer hospital between Jan. 1990 and Aug. 2012. All the pa- tients received bilateral salpingo-oophoreetomy. Clinical and histopathologic data were reviewed to determine the risk factors of ovarian metastasis by analyzing the characteristic factors of the clinicopathological features. Results: Overall, Ovarian metastasis was detected in 16 patients (4.98%). The median age was 52+_13 years old. Univariate analysis indicated that uterine cor- pus involvement, lymph nodes metastasis, deep stromal invasion, FIGO stage more than stage I a, parametrium involvement were the risk factors of ovarian metastasis. But muhivariate analy- sis showed parametrium involvement was the only independent predictor of ovarian metastasis. The 2-year and 5-year survival rate was 81.3% and 62.5% , respectively. Conclusions:Ovarian metastasis occurred more frequently in patients with adenocarcinoma than in patients with squa- mous cell carcinoma. Ovarian preservation in those with increased risks of ovarian metastasis should be reconsidered.
出处
《现代妇产科进展》
CSCD
北大核心
2015年第7期501-503,共3页
Progress in Obstetrics and Gynecology
关键词
宫颈腺癌
卵巢转移
Cervical adenocarcinoma
Ovarian metastasis