肝硬化患者应用阿德福韦酯治疗导致低磷性软骨病1例
被引量:1
摘要
慢性乙型肝炎(chronic hepatitis B,CHB)是全球性公共卫生问题[1,2],若不及时的抗病毒治疗可进展成肝硬化,甚至肝癌。为了减缓疾病的进展,抗病毒治疗是关键。阿德福韦酯以其相对低廉的价格和低耐药率在我国抗病毒药物的市场中占有重要的地位。我们报道1例肝硬化的患者在服用阿德福韦酯治疗导致低磷性骨病。
出处
《中国肝脏病杂志(电子版)》
CAS
2015年第2期111-112,共2页
Chinese Journal of Liver Diseases:Electronic Version
参考文献8
-
1Lok AS, McMahon B1. Chronic hepatitis B: update of recommendations[J]. Hepatology,2004,39:857 -861.
-
2Lai CL, Ratziu V, Yuen MF, et al. Viral hepatitis B[J]. Lancet, 2003,362:2089-2094.
-
3Jung YK, Yeon JE, Choi JH, et al. Fanconi's syndrome associated with prolonged adefovir dipivoxil therapy in a hepatitis B virus patient[J]. Gut and Liver,2010,4:389-393.
-
4Hamnvik OP, Becker CB, Levy BD, et al. Clinical problem-solving. Wasting away[J]. N Engl J Med,2014,370:959-966.
-
5Hannon H, Bagnis CI, Benhamou Y, et al. The renal tolerance of lowdose adefovir dipivoxil by lamivudine-resistant individuals co-infected with hepatitis B and HIV[J]. Nephrol Dial Transplant,2004,19:386-390.
-
6Izzedine H, Hulot JS, Launay- Vacher V, et al. Renal safety of adefovir dipivoxil in patients with chronic hepatitis B: two double-blind, randomized, placebo-controlled studies[J]. Kidney Int,2004,66:1153- 1158.
-
7Jeong HJ, Lee JM, Lee TH, et al. Two Cases of Hypophosphatemic Osteomalacia After Long-term Low Dose Adefovir Therapy in Chronic Hepatitis B and Literature Review[J]. J Bone Metab,2014,21:76-83.
-
8林清锋,潘凡,洪富源,潘晨.阿德福韦酯致Fanconi综合征及低磷性软骨病1例[J].中华肝脏病杂志,2014,22(10):779-780. 被引量:3
二级参考文献5
-
1Jung YK, Yeon JE, Choi JH, et al. Fanconi's syndrome associated with prolonged adefovir dipivoxil therapy in a hepatitis B virus patient[J]. Gut Liver, 2010, 3: 389-393.
-
2Hamnvik OP, Becker CB, Levy BD, et al. Clinical problem-solving. Wasting away[J]. N Engl J Meal, 2014, 370: 959-966.
-
3赵海芹,韩文梅.阿德福韦酯致肾损害2例[J].药物不良反应杂志,2010,12(3):213-214. 被引量:18
-
4孙晓方,张化冰,李新萍,夏维波,邢小平,孟迅吾.阿德福韦酯导致低血磷性骨软化症一例并文献复习[J].中华内科杂志,2011,50(9):754-757. 被引量:45
-
5李玲,董光富,张晓,谢悦胜.阿德福韦酯致Fanconi综合征和低磷性骨软化症并进行性肌无力1例[J].南方医科大学学报,2011,31(11):1956-1956. 被引量:42
共引文献2
-
1王俊娜,黄文祥.77例阿德福韦酯致范可尼综合征回顾性分析[J].中国新药杂志,2016,25(19):2277-2280. 被引量:7
-
2李力,郭丽颖,李秋伟,苗静,翁奉武,贾建伟,徐宗佩.抗乙型肝炎病毒核苷(酸)类似物肾损害的研究进展[J].医学综述,2018,24(19):3761-3765.
同被引文献19
-
1Fontana RJ. Side effects of long-term oral antiviral therapy for hepatitis[J]. Hepatology,2009,4 9:185-195.
-
2Izzedine H, Hulot JS, Launay-Vacher V, et al. Renal safety of adefovir dipivoxil in patients with chronic B:two doubleblind, randomized, placebo-controlled studies[J]. Kidney Int,2004.66:1153-1158.
-
3Tamori A, Enomoto M, Kobayashi S, et al. Add-on combination therapy with adefovir dipivoxil induces renal impairment in patients with lamivudine-refractory hepatitis B virus[J]. J Viral Hepat,2010,17:123-129.
-
4Wong T, Girgis CM, Ngu MC, et al. Hypophosphattemic osteomalacia after low-dose adefovir dipivoxil therapy for hepatitis B[J]. J Clin Endocrinol Metab,2010,95:479-480.
-
5Kwon J, Ahn SY, Ko SY, et al. A case of osteomalacia related to adfovir in a patient with chronic hepatitis B[J]. Korean J Gastroenterol,2010,56:117-120.
-
6Izzedine H, Launay-Vacher V, Deray G. Antiviral drug-induced nephrotoxicity[J]. Am J Kidney Dis,2005.45:804-817.
-
7Bichet DG. Inherited disorders of the renal tubule/brenner BM. Brenaer & rector' s the kidney[M]. 8th ed. Philadelphia: Saunders,2008:1390-1393.
-
8Kim DH, Sung DH, Min YK. Hypophosphatemic osteomalacia induced by low-dose adefovir therapy: focus on manifestations in the skeletal system and literature review[J]. J Bone Miner Metab,2013,31:240-246.
-
9Kim YJ, Cho HC, Sinn DH, et al. Frequency and risk factors of renal impairment during long-term adefovir dipivoxil treatment in chronic hepatitis B patients[J]. J Gastroenterol Hepatol,2012,27:306-312.
-
10Tanaka M, Suzuki F, Seko Y, et al. Renal dysfunction and hypophosphatemia during long-term lamivudine plus adefovir dipivoxil therapy in patients with chronic hepatitis B[J]. J Gastroenterol,2013,49:470-480.
二级引证文献4
-
1李新文,范玉琛,邢延清,韩利岩,石磊,张秀华,于淑凤,冯宁宁.阿德福韦酯联合拉米夫定或恩替卡韦治疗慢性乙型肝炎和肝硬化出现肾损害后的处理[J].中国临床医生杂志,2019,47(5):542-546. 被引量:18
-
2冯剑春,王华雨,谢群,沈毅.阿德福韦酯致范可尼综合征并发低血磷性骨软化症的肾毒性研究[J].胃肠病学和肝病学杂志,2021,30(4):432-435. 被引量:5
-
3唐长征.阿德福韦酯导致HBV患者发生低磷血症及骨关节疼痛分析[J].海峡药学,2021,33(4):217-218.
-
4季琴,席巍,沈毅.阿德福韦酯致低血磷性骨软化症5例临床分析[J].肝脏,2021,26(8):924-927. 被引量:1
-
1罗光荣.警惕治疗乙肝的核苷酸药物引发软骨病[J].家庭医药(就医选药),2015,0(10):40-41.
-
2尹有宽.“乙肝”长期抗病毒:需警惕“低磷软骨病“[J].大众医学,2014(9):26-26.
-
3乐忠宏.低磷软骨病13例误诊分析[J].中国现代医药杂志,2012,14(5):99-100. 被引量:5
-
4王金山.小儿感冒莫麻痹[J].家庭医学(上半月),2008(3):14-14.
-
5吴凤霞,马英奎.维生素D依赖性佝偻病或软骨病1例报告[J].国际医药卫生导报,2004,10(20):84-84.
-
6蒋瑾瑾.宝宝软骨病如何防与治[J].家庭用药,2001(6):25-25.
-
7SU Ji-mei,LI Yun,YE Xiao-wei,WU Zhi-fang.Oral findings of hypophosphatemic vitamin D-resistant rickets:report of two cases[J].Chinese Medical Journal,2007(16):1468-1470.
-
8金京玉,孙飞,王刚,杨金水,罗贵,马华,赵征,冯丽霞,王炎焱,赵伟,张江林,朱剑,黄烽.误诊为脊柱关节炎的低磷软骨病26例临床分析[J].中华内科杂志,2014,53(11):847-851. 被引量:6
-
9金世鑫.钙磷代谢疾病[J].中国骨质疏松杂志,2001,7(4):346-360. 被引量:12
-
10马志文,于晓东,杨桂芳,贾玲.药源性软骨病1例[J].黑龙江医学,1995,0(7):46-46.