紫苏百合龙骨牡蛎汤合二夏汤治疗慢性失眠68例临床观察

Treatment of 68 cases of Insomnia by Zisu-Baihe-Longgu-Muli Decoction with Erxia Decoctio

目的:观察紫苏百合龙骨牡蛎汤合二夏汤加减治疗失眠的临床疗效。方法:选取失眠患者68例,按患者服药的依从性分为对照组34例和观察组34例。对照组给予艾司唑仑片治疗,观察组给予紫苏百合龙骨牡蛎汤合二夏汤加减治疗。结果:对照组总有效率为73.52%,观察组总有效率为91.17%,两组总有效率有显著性差异(P<0.01);对照组不良反应发生率为44.12%,观察组不良反应发生率为5.59%,观察组明显低于对照组(P<0.01)。结论:紫苏百合龙骨牡蛎汤合二夏汤加减治疗失眠疗效显著,且不良反应发生率低。

Objective：To observe the clinical curative effect of Zisu-Baihe-Longgu-Muli Decoction with Erxia Decoctio on insomnia. Methods：68 patients with insomnia were divided into the control group and the observation group,34 cases in each group.The patients in the control group were treated with small estazolam tablets,while the ones in the observation group were given Zisu-Baihe- Longgu-Muli Decoction with Erxia Decoctio for oral administration.Results：The total effective rate of the control group was 73.52%,while that of the observation group was 91.17%,and the control group was obviously lower than the observation group （P〈0.01）;The side-effect incidence rate of the control group was 44.12%,while that of the observation group was 5.59%,and the observation group was obviously lower than the control group（P〈0.01）. Conclusion：Zisu-Baihe- Longgu-Muli Decoction with Erxia Decoctio has good curative effect on insomnia with low side-effect incidence rate.