降脂化浊汤联合地衣芽胞杆菌治疗非酒精性脂肪性肝炎临床研究

The Clinical Research into Non-Alcoholic Steatohepatitis Treated with Jiangzhi Huazhou Decoction in Combination with Bacillus Licheniformis

目的:观察降脂化浊汤联合地衣芽胞杆菌治疗非酒精性脂肪性肝炎的临床疗效。方法:选取本院90例非酒精性脂肪性肝炎患者作为研究对象,随机分为对照组和治疗组各45例,对照组给予地衣芽胞杆菌治疗,治疗组给予降脂化浊汤治疗,两组疗程均为8周,比较两组患者临床疗效。结果:两组患者治疗后中医证候积分、肝功能血清转氨酶(AST、ALT、GGT)及血脂(T G,TC)水平均较治疗前明显改善(P<0.05),但同期比较治疗组较对照组改善更明显(P<0.05)。结论:降脂化浊汤联合地衣芽胞杆菌治疗非酒精性脂肪性肝炎可有效降低患者血脂水平、改善肝功能,减轻临床症状。

Objective： To observe the clinical curative effect of Jiangzhi Huazhou Decoction （JZHZD） in combination with bacillus licheniiormis on non-alcoholic steatohepatitis （NASH）. Methods： Ninety patients with NASH who were treated in our hospital were chosen as the research objects and were randomly divided into the control group and the treatment group, with 45 cases in each grot, p. The ones in the cont,＇ol group were treated with bacillus licheniformis, while the ones in the treatment group were giv- en JZHZD. After 8 weeks＇treatment, the clinical curative effects of both groups were compared. Results： After the treatment, TCM symptom score, AST, AI,T, GGT, T G level and TC level of blood lipids）were greatly improved（ P 〈 0.05 ）; However, compared at the same time, the improved degree of the treatment group was more obviously than the control group （ P 〈 0.05 ）. Conclusian ： JZHZD in combination with bacillus hcheniformis can greatly reduce the blood lipids of patients with NASH, improve their liver function, and reduce the clinical symptoms.