膝痹汤合舒膝散治疗膝关节退行性关节炎临床研究

The Clinical Research into Degenerative Arthritis of Knee Joint Treated with Xibi Decoction in Combination with Shuxi Powder

目的:观察膝痹汤合舒膝散治疗膝关节退行性关节炎的临床疗效。方法:选择2013年6月—2014年6月在本院接受治疗的66例膝关节退行性关节炎患者,随机分为观察组34例和对照组32例,对照组内服抗骨增生胶囊、外用骨科外洗二方予以治疗,观察组患者内服膝痹汤、外用舒膝散治疗。观察两组患者的临床疗效、WOMAC评分、VAS评分以及不良反应情况。结果:观察组有效率为88.2%,对照组有效率为65.6%,两组有效率比较,差异有显著性(P<0.05);两组患者的VAS评分都较治疗前明显改善(P<0.05),但两组之间比较差异不具有统计学意义(P>0.05);两组患者WOMAC评分都较治疗前明显改善(P<0.05),但观察组患者改善更加明显(P<0.05);两组患者治疗过程中均未发生较为明显不良反应。结论:膝痹汤合舒膝散治疗膝关节退行性关节炎疗效显著。

Objective： To observe the clinical curative effect of Xibi Decoction （XBD） in combination with Shuxl Powder （SXP） on degenerative arthritis of knee joint. Methods ： Sixty-six patients with degenerative arthritis of knee joint who were treated in our hospital from Jun. 2013 to Jun. 2014 were chosen and randomly divided into the observation group and the control group, with 34 and 32 cases in each group respectively. The ones in the control group were given Kanggu Zengsheng Capsule （KGZSC） for oral administration and Guke Waixi Erfang （GKWXEF） for external use, while the ones in the observation group were given XBD for oral administration anti SXP for external use. Then the clinical curative effect, WOMAC score, VAS score, and the adverse reactions in both groups were observed. Results： The effective rate of the observation group was 88.2%, while that of the control group was 65.6% ; And the difference between them had significance （ P 〈 0. 05 ）. After the treatment, VAS scores of both groups obviously improved （ P 〈0.05 ）, but the difference between two groups had no statistical significance（ P 〉0.05 ）. After the treatment, WOMAC scores of both groups obviously improved （P 〈 0. 05）, but the improved degree of the observation group was more obviously than that of the control group（ P 〈0.05）. There was no obvious adverse reactions in both groups during tile treatment process. Conclusion ： XBD in combination with SXP has remarkable clinical curative effect on degenerative arthritis of knee joint.