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上海部分地区非瓣膜性心房颤动患者使用华法林抗凝治疗现状调查 被引量:6

Antithrombotic therapy with warfarin in patients with non-valve atrial fibrillation in the real world:data from Shanghai Tongji hospital
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摘要 目的:通过对上海市同济医院住院患者的华法林使用情况进行横断面调查,了解非瓣膜性心房颤动患者华法林使用现状。方法:入选2012年1月至2013年12月收治于我院的所有永久性心房颤动患者。使用CHADS2和CHA2DS2-VASc系统分别评分。统计和比较中、高危患者使用华法林实际情况。结果:共入选2 451例非瓣膜性心房颤动患者,1 716例(70.0%)患者CHADS2评分≥2分,其中服用华法林的有565例(32.92%);2 113例(86.1%)患者CHA2DS2-VASc评分≥2分,其中服用华法林的有569例(26.93%)。结论:临床实践中,心房颤动中、高危患者华法林使用率严重不足。 Objective: To describe guideline adherence and oral antithrombotic therapy with warfarin rates among real-life patients with non valve atrial fibrillation (NVAF) through a retrospective cohort study. Methods: The patients with permanent NVAF hospitalized in Shanghai Tongji Hospital from Jan 2012 to Dec 2013 were recruited. Proportion of warfarin usage was estimated in those patients with known NVAF who should be eligible for anticoagulation therapy. Analysis of the usage of warfarin was performed in middle-high risk patients. Results: Of 2 451 patients, 1 716 (70. 0%) were at intermediate and high risks according to CHADS2, and 2 113 (86. 1%) according to CHA2DS2 VASc. Only 565(32. 92%) and 569(26. 93%) were on warfarin according to CHADS2 and CHA2DS2-VASc, respectively. Conclusion: Warfarin has been significantly under-used in patients with known NVAF in real life.
出处 《国际心血管病杂志》 2015年第4期288-290,共3页 International Journal of Cardiovascular Disease
关键词 心房颤动 口服抗凝药物 华法林 Atrial fibrillation Anticoagulation Warfarin
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  • 1Camm AJ, Lip GY, De Caterina R, et al. 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation+developed with the special contribution of the European Heart Rhythm Association[J]. Europace , 2012,14 (10): 1385-1413.
  • 2Chang KC, Wang YC, Ko PY, et al. Increased risk of firstever stroke in younger patients with atrial fibrillation not recommended for anti thrombotic therapy by current guidelines: a population-based study in an East Asian cohort of 22 million people [J]. Mayo Clin Proc, 2014, 89 (11): 1487-1497.
  • 3Schweizer PA, Becker R, Katus HA, et al. Dronedarone , current evidence for its safety and efficacy in the management of atrial fibrillation[J]. Drug Des Devel Ther,2011 ,5:27-39.
  • 4January CT, Wann LS, Alpert]S, et al. 2014 AHA/ ACC/ HRS guideline for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the Heart Rhythm Society [J]. Circulation, 2014, 130(23) :2071-2104 .
  • 5Huang K, Khan N, Kwan Av et al. Socioeconomic status and care after stroke: results from the Registry of the Canadian Stroke Network[J]. Stroke,2013,44(2) :477-482.
  • 6Mercaldi CJ, Ciarametaro M, Hahn B,et al. Cost efficiency of anticoagulation with warfarin to prevent stroke in medicare beneficiaries with nonvalvular atrial fibrillation [J]. Stroke, 2011,42(1):112-118.
  • 7Partington SL, Abid S, Teo K, et al. Pre-admission warfarin use in patients with acute ischemic stroke and atrial fibrillation: The appropriate use and barriers to oral anticoagulant therapy [J]. Thromb Res, 2007, 120 (5): 663-669.
  • 8周自强,胡大一,陈捷,张仁汉,李奎宝,赵秀丽.中国心房颤动现状的流行病学研究[J].中华内科杂志,2004,43(7):491-494. 被引量:1398

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共引文献1397

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  • 1Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham study [J]. Stroke, 1991,22(8) :983-988.
  • 2Lau DH, Kalman J, Sanders P, et al. Management of recent- onset sustained atrial fibrillation: pharmacologic and nonpharmacologic strategies [J]. Clin Ther, 2014, 36 (9): 1151-1159.
  • 3Camm AJ, Lip GY, De Caterina R, et al. 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation. Developed with the special contribution of the European Heart Rhythm Assoeiation[J]. Eur Heart J,2012,33(21):2719 -2747.
  • 4Van Staa TP, Setakis E, Di Tanna GI., et al. A comparison of risk stratification schemes for stroke in 79, 884 atrial fibrillation patients in generalpractiee [J].J Thromb Haemost, 2011, 9(1 ) :39-48.
  • 5Rahman F, Kwan GF, Benjamin EJ. Global epidemiology of atrial fibrillation[J]. Nat Rev Cardiol, 2014, 11 ( 11 ) : 639-654.
  • 6Kneeland PP, Fang MC. Current issues inpatient adherence and persistence: focus on anticoagulants for the treatment and prevention of thromboembolism[J]. Patient Prefer Adherence, 2010,4(1 ) : 51-60.
  • 7Lip GY, Kamath S,Jafri M, et al. Ethnic differences in patient perceptions of atrial fibrillation and anticoagulation therapy: the West Birmingham Atrial Fibrillation Project[J]. Stroke, 2002,33(1) :238- 242.
  • 8Razouki Z, Ozonoff A, Zhao S, et al. Pathways to poor anticoagulation control[J]. J Thromb Haemost, 2014,12 ( 5 ) : 628-634.
  • 9张超,刘旭.解读欧洲心脏病协会首次独立提出的心房颤动指南[J].国际心血管病杂志,2010,37(6):383-384. 被引量:3
  • 10黄煜.低强度华法林抗凝治疗脑卒中风险房颤患者的临床研究[J].当代医学,2011,17(9):139-140. 被引量:17

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