左甲状腺素钠对妊娠合并甲状腺功能减退患者转归的影响

Efficacy of Levothyroxine Sodium Pregnancy Outcome in Patients With Thyroid Function Loss

目的：研究左甲状腺素钠对妊娠合并甲状腺功能减退患者归转的影响。方法选取2012年1月～2014年5月期间在我院进行甲状腺功能检查的12周妊娠期孕妇180例，其中60例妊娠期孕妇的甲状腺功能减退，将其归为实验组，60例妊娠期孕妇为亚临床甲状腺功能减退，将其归为观察组，另60例妊娠期孕妇的甲状腺功能正常，将其归为对照组，给予实验组孕妇和观察组孕妇左甲状腺素钠进行治疗，比较三组孕妇的妊娠情况。结果实验组、观察组及对照组孕妇在分娩孕周、新生儿重量、新生儿窒息、妊娠期合并疾病等方面均无差异，不存在统计学意义（P＞0.05）。结论在妊娠早期对孕妇进行甲状腺功能检查，并及时给予左甲状腺素钠对甲状腺功能减退孕妇进行治疗，能使甲状腺功能减退孕妇得到正常的妊娠结局。

Objective To study the effect of the left thyroid hormone on the patients with pregnancy complicated with hypothyroidism.Methods From January 2014 to May 2012 in our hospital for thyroid function examination of 12 weeks pregnant women,180 cases,including 60 cases of pregnant women with hypothyroidism,to the experimental group,60 cases of pregnant women with subclinical hypothyroidism, the other 60 cases of pregnant women with normal thyroid function,the control group,the experimental group and the observation group were treated with sodium,compared with three groups of pregnant women.Results In the experimental group,the observation group and the control group,the pregnant women in the delivery gestational age,neonatal weight,neonatal asphyxia,pregnancy and other diseases,such as no difference,no statistical significance（P〉0.05）.Conclusion In the early pregnancy,thyroid function examination for pregnant women,and to give the left thyroid function in pregnant women for treatment,can make the thyroid function of pregnant women get normal pregnancy outcome.