肝硬化糖代谢异常相关因素分析

Cirrhosis of abnormal glucose metabolism related factors

目的探讨肝硬化与糖代谢异常的关系。方法对本院73例肝硬化患者,观察不同级别肝损害与糖代谢异常相关性,以及糖代谢异常时肝硬化并发症的相关因素进行回顾性分析。结果根据肝硬化肝功能Child-Pugh计分,不同级别肝功能患者血糖异常发生率为67.12%,差异有统计学意义(P<0.05);肝硬化在糖代谢异常的情况下,患者死亡的发生、消化道出血、肝性脑病的并发症,构成比分别为79.6%、85.7%和59.2%,经x2检验,差异有统计学意义(P<0.05)。结论肝硬化可影响糖代谢,肝硬化糖代谢异常则在一定程度上能反映肝细胞受损的严重程度,并与疾病预后密切相关。

Objective Explore the relationship between cirrhosis and abnormal glucose metabolism.Methods 73 cases of hospital patients with cirrhosis,observe the different levels of liver damage and abnormal glucose metabolism correlation,and the related factors of abnormal glucose metabolism during the complications of liver cirrhosis were retrospectively analyzed.ResultsAccording to the liver function of liver cirrhosis Child-Pugh score,blood glucose level in patients with abnormal liver function occurred in 67.12%,with statistical significance（P〈0.05）;Abnormal glucose metabolism in liver cirrhosis cases,complications occurred in patients with death,gastrointestinal hemorrhage,hepatic encephalopathy,constituent ratio in 79.6%,85.7% and 59.2%,Byχ2test,the difference was statistically significant（P〈0.05）. Conclusion Cirrhosis can affect glucose metabolism,abnormal glucose metabolism in cirrhosis is in a certain extent can reflect the severity of liver cell damage,and is closely related to the prognosis of the disease.