摘要
肥胖是威胁人类健康的重要慢性病之一,肠道菌群结构失调在其发生、发展中起着重要作用。肠道菌群可促进能量吸收、调控脂肪的合成和储存、诱导机体慢性低度炎症,最终导致肥胖及后续的代谢障碍。阐明肠道菌群与肥胖的关系及作用机制可能会为肥胖的防控与治疗提供新的靶点。
Obesity has become one of the important chronic disease which threatens the human health, and gut microbiota play an important role in the occurrence and development of obesity. Proposed mechanisms for the role of gut microbiota include the increase of energy harvest from the diet, regulation synthesis and storage of fat, induction chronic low-grade inflammation, eventually leading to obesity and subsequent metabolism disorders. Elucidating the mechanism of the intestinal flora in obesity may provide new targets for the prevention and treatment of obesity.
出处
《中国食品卫生杂志》
2015年第4期472-475,共4页
Chinese Journal of Food Hygiene
关键词
肠道菌群
肥胖
能量平衡
慢性低度炎症
Gut microbiota
obesity
energy homeostasis
chronic low-grade inflammation
