膝骨性关节炎关节镜清理手术后辅以滑膜炎颗粒治疗的临床观察

Clinical observation of adjuvant Huamoyan granule after arthroscopy debridement in the treatment of knee osteoarthritis

目的探究应用滑膜炎颗粒对膝骨性关节炎关节镜清理手术后进行辅助治疗的临床效果。方法 162例已经进行关节镜清理手术的患者,随机分为观察组和对照组,各81例。观察组患者采用滑膜炎颗粒进行术后辅助治疗,对照组患者采用酮基布洛芬进行术后治疗。观察并分析两组患者的临床治疗效果。结果两组术后视觉模拟量表(VAS)评分比较,差异无统计学意义(P>0.05);随访期间观察组的VAS评分低于对照组,差异有统计学意义(P<0.05);两组随访期间VAS评分较术后均明显降低,差异有统计学意义(P<0.05);观察组总有效率96.3%明显高于对照组82.7%,差异有统计学意义(P<0.05);观察组在治疗过程中没有出现不良反应,对照组在治疗过程中有8例患者出现轻度的胃部不适,及时治疗后,症状均消失。结论应用滑膜炎颗粒对膝骨性关节炎关节镜清理手术后进行辅助治疗临床效果显著,起效较快而且不良反应较少,值得在临床上推广。

Objective To investigate clinical effect by Huamoyan granule after arthroscopy debridement in adjuvant therapy of knee osteoarthritis.Methods There were 162 patients receiving arthroscopy debridement. They were randomly divided into observation group and control group, with 81 cases in each group. The observation group received Huamoyan granule for adjuvant therapy after arthroscopy debridement, and the control group received ketoprofen for postoperative treatment. Clinical effects of the two groups were observed and analyzed.Results There was no statistically significant difference of postoperative visual analogue scale （VAS） scores between the two groups （P〉0.05）. During follow-up, the observation group had lower VAS score than the control group, and their difference had statistical significance （P〈0.05）. Both groups had lower VAS scores during follow-up than those after operation, and their difference had statistical significance （P〈0.05）. The observation group had much higher total effective rate as 96.3% than 82.7% of the control group, and their difference had statistical significance （P〈0.05）. There was no case with adverse reactions in the observation group, while in the control group there were 8 cases with mild stomach discomfort. After timely treatment, all adverse symptoms were healed.Conclusion Implement of Huamoyan granule for adjuvant therapy after arthroscopy debridement provides precisely clinical effect for knee osteoarthritis. This method has quick onset time and few adverse reactions, and it is worthy of clinical promotion.