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尿酸对缺血性卒中的神经保护作用 被引量：5

Neuroprotecfive effect of uric acid in ischemic stroke
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摘要 高尿酸血症与高血压、糖尿病、冠心病等密切相关。不过，大量研究显示，尿酸作为一种天然的抗氧化剂，具有强有力的抗氧化作用，可增强机体总抗氧化能力，清除组织内的自由基，降低氧化应激水平，改善卒中患者转归。通过探讨尿酸对缺血性卒中的神经保护作用，可能为卒中的治疗提供新的靶点。 Hyperuricemia is closely associated with hypertension, diabetes, coronary heart disease. However, numerous studies have shown that as a natural antioxidant, uric acid has a strong antioxidant effect. It can enhance the body＇s overall antioxidant capacity, scavenge free radicals in tissue, decrease the level of oxidative stress, and improve the outcomes in patients with stroke. It may provide a new target for the treatment of stroke through investigating the neuroprotective effect of uric acid on ischemic stroke.
作者 卢丹丹 王京 王佩
机构地区 保定市第一中心医院神经内三科
出处 《国际脑血管病杂志》 2015年第7期546-549,共4页 International Journal of Cerebrovascular Diseases
关键词 卒中 脑缺血 尿酸 氧化性应激 神经保护药 Stroke Brain Ischemia Uric Acid Oxidative Stress Neuroprotective Agents
分类号 R743.3 [医药卫生—神经病学与精神病学]
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参考文献35

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二级参考文献20

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国际脑血管病杂志
2015年 第7期

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