原发性视网膜色素变性伴发青光眼的研究进展

Research progress on primary retinitis pigmentosa combined with glaucoma

原发性视网膜色素变性(retinitis pigmentosa,RP)是一类由于光感受器细胞和色素上皮细胞功能丧失所致遗传性致盲眼病。临床研究发现,RP除了可以单独发病以外,往往可以合并其他眼部疾病,其中,RP合并青光眼由于对视力的严重损害不断被国内外文献所报道。该文分析国内外发表的RP合并青光眼的病例资料,总结了该类患者的相关性、临床特征以及发病机制等,并对该类患者的病情控制提出了可行性的建议,但是,在发病机制和治疗方面仍有待进一步深入研究。

Primary retinitis pigmentosa is an inherited eye disease caused by abnormalities of photoreceptors or retinal pigment epithelium, which can lead to blindness. Clinical studies have found that retinitis pigmentosa usually coexists with other ocular features instead of attacking alone. Among these features, retinitis pigmentosa combined with glaucoma has drawn great attention at home and abroad due to severe damage to visual acuity. So we collected and analyzed the cases previously published, and summarized the clinical characteristics of these patients and offered feasible advices to control the progress of disease. But it still needs further exploration in both pathogenesis and treatment.