提高支气管哮喘控制率的药学实践

The Pharmaceutical Practice of Clinical Pharmacists in Patients with Bronchial Asthma

目的探讨临床药师对支气管哮喘患者开展药学服务的作用。方法将120例支气管哮喘患者随机分为干预组和对照组,每组60例,干预组实行药学服务干预措施,对照组给予常规的治疗和护理。出院后1个月和6个月对患者进行治疗评估,统计其用药依从性变化和哮喘控制程度。结果干预组干预后1个月和6个月用药依从性明显提高,分别为68.33%和61.67%,P<0.01差异有统计学意义。对照组干预后1个月有统计学差异(P<0.05),而6个月后无统计学差异(P>0.05)。两组在干预后1个月和6个月ACT得分均比干预前增高,P<0.01。两组在出院后6个月ACT得分有差异(P<0.01)。结论开展药学服务可提高支气管哮喘患者的长期用药依从性和哮喘控制率。

Objective To investigate the clinical study conducted in patients with bronchial asthma pharmacist pharmacy services. Methods 120 cases of bronchial asthma were randomly divided into intervention group and control group. Intervention group was provided pharmacy services interventions and control group was received conventional treatment and care. lmonth and 6 months after treatment of patients assessed. Changes in medication adherence and asthma control were analyzed. Results The medication compliance of intervention group was improved significantly, one month 68.33% and six months 61.67%.The difference was statistically significant （P〈0.01）.After 1 month there was significant difference in the control group （P〈0.05）.But there was no significant difference （P〉0.05） 6 months after. In two groups of 1 months and 6 months after intervention ACT scores are higher than before （P〈0.01）.ACT scores are different of two groups in 6 months after intervention（P〈0.01）.Conclusion Pharmaceutical care of patients with bronchial asthma can improve long-term medication adherence and asthma control.