运动负荷核素心肌灌注显像与冠状动脉造影诊断老年人冠状动脉病变的对比研究

Comparison of stress myocardial perfusion imaging with coronary angiography in detection of coronary artery disease in the elderly

目的比较运动负荷核素心肌灌注显像(MPI)与冠状动脉造影(CAG)诊断老年人冠状动脉病变(CAD)的临床价值。方法 35例临床疑诊冠状动脉粥样硬化性心脏病(冠心病)的高龄患者行MPI及CAG检查,对比分析检查所见及诊断结论。结果 35例高龄患者中CAG阳性20例,MPI诊断敏感度、特异性、阳性预测值、阴性预测值分别为75%,80%,83%,71%。结论核素MPI反映心肌摄取显像剂的能力,与相应血管通畅情况和心肌细胞活性有关,联合CAG可以达到全面准确诊断冠心病的目的。

Objective To investigate clinical value of myocardial perfusion imaging（MPI）and coronary angiography（CAG） in the detection of coronary artery disease（CAD） in elderly patients. Methods Thirty-five patients were examined by MPI and CAG. All data were analyzed and compared. Results Twenty patients showed abnormol signs in CAG. The sensitivity,specificity,positive and negative predictive values of MPI in detecting CAD was 75%,80%,83%and 71% respectively. Conclusion MPI can display uptake function of heart cell,connected with coronary arteries unobstructed and cell activity. CAD can be diagnosed correctly and totally by using MPI and CAG synthetically.