摘要
制备丁香油口腔膜剂并对其进行初步的质量评价。以丁香油为主药,聚乙烯醇、羧甲基纤维素纳、甘油为成膜材料制备丁香油口腔溃疡膜;以成膜性等性能作为考察指标筛选出最佳处方,并进行质量评价。丁香油口腔溃疡膜的最佳处方为聚乙烯醇2.7g,羧甲基纤维素钠0.3g,甘油0.5g,丁香油0.5g。由最佳处方制备出来的丁香油口腔溃疡膜成膜性好,表面光滑,厚度均匀一致,颜色均匀,质地柔软,韧性好。制备丁香油口腔膜剂在外观、重量差异度、溶解时间等方面均较佳,为下一步开展药效实验奠定较好的研究基础。
To make the clove oil oral ulcer film and to evaluate the quality of clove oral ulcer fill. , the dove oil oral ulcer fill was prepared using dove oil, polyvinyl alcohol, sodium earboxymethyl cellulose, glycerin as fill materials. To make the quality evaluation of dove oil oral ulcer fill, including weight difference degree, dissolution time. The film forming ability, softness, smoothness, thickness, color and toughness of elove oil oral ulcer fill was prepared well. The appearance, weight difference degree, dissolution time was prepared well, so laid a good foundation for further research of efficaey experiments.
出处
《山东化工》
CAS
2015年第16期22-23,共2页
Shandong Chemical Industry
基金
广东省自然科学基金(S2012010010489)
广东省医学科研基金(A2013688)