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抑郁症生物学基础新进展及药物治疗新靶点(二) 被引量:3

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摘要 本综述对抑郁症各发病假说之间的关联进行深入探讨,以期发现抑郁症发生过程中的共同通路和关键靶点。通过对抑郁症疾病信号网络的整合,我们发现脑源性神经生长因子的功能失调和由此导致的神经细胞凋亡是抑郁症发病机制的终末环节,而最新的研究结果也证实增强脑源性神经生长因子的功能确实可以显示出快速而持久的抗抑郁效果。
出处 《临床精神医学杂志》 2015年第4期282-284,共3页 Journal of Clinical Psychiatry
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